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The Brainteaser Ontology

Release February 2022

This version:
https://w3id.org/brainteaser/ontology
Latest version:
https://w3id.org/brainteaser/ontology
Revision:
1.0
Authors:
Manuel Bettin, (University of Padua)
Giorgio Maria Di Nunzio, (University of Padua)
Dennis Dosso, (University of Padua)
Guglielmo Faggioli, (University of Padua)
Nicola Ferro, (University of Padua)
Nicola Marchetti, (University of Padua)
Gianmaria Silvello, (University of Padua)
Contributors:
Members of the Brainteaser project, Brainteaser H2020
Publisher:
Brainteaser project
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the grant agreement No GA101017598
Download serialization:
JSON-LD RDF/XML N-Triples TTL
License:
https://creativecommons.org/licenses/by-sa/4.0/ License
Visualization:
Visualize with WebVowl
Cite as:
Manuel Bettin, Giorgio Maria di Nunzio, Dennis Dosso, Guglielmo Faggioli, Nicola Ferro, Nicola Marchetti, Gianmaria Silvello 2022. The Brainteaser Ontology, v1.0. https://w3id.org/brainteaser/ontology

Ontology Specification Document

Introduction back to ToC

This webpage describes the design and development of the BRAINTEASER Ontology (BO) whose purpose is to jointly model both Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS).

The BO serves multiple purposes:

  • to provide a unified and comprehensive conceptual view about ALS and MS, which are typically dealt with separately, allowing us to coherently integrate the data coming from the different medical partners in the project;
  • to seamlessly represent both retrospective data and prospective data, produced during the lifetime of BRAINTEASER
  • to allow for sharing and re-using the BRAINTEASER datasets according to Open Science and FAIR principles.

BRAINTEASER Ontology approach

The BO is innovative since it relies on very few seed concepts - Patient, Clinical Trial, Disease, Event - which allow us to jointly model ALS and MS and to grasp the time dimension entailed by the progression of such diseases.

Indeed, the core idea is that a Patient participates in a Clinical Trial, suffers from some Diseases, and undergoes Events. These Events are different in nature and cover a wide range of cases, e.g. Onset, Pregnancy, Symptom, Trauma, Diagnostic Procedure (like evoked potentials or ALS-FRS questionnaires) Therapeutic Procedure (like Mechanical Ventilation for ALS or Disease-Modifying Therapy for MS), Relapse, and more. Overall, this event-based approach allows us to model ALS and MS in an unified way, sharing concepts among these two diseases, and to track what happens during their progression. Details of the design and functioning of the BO are provided in the next sections of this deliverable.

Role of the BRAINTEASER Ontology

The BO plays an important role in the overall BRAINTEASER architecture, shown in Figure 1. Indeed, it informs the implementation of the BRAINTEASER Semantic Data Cloud since the data contained here will be represented according to the BO, i.e., they will be an instance of the BO.

In Figure 1 it is possible to see that all the data will be anonymized prior to being represented in the BO. This holds true for both the retrospective data, i.e., the data already held by clinical partners on the right of the figure, and the prospective data, i.e., the new data that will be collected during the project lifetime on the left.

Brainteaser architecture
Figure 1.The BRAINTEASER ontology and its role in the overall BRAINTEASER architecture.

The data held in the BRAINTEASER Semantic Data Cloud, exported in a suitable format, will then be used to train the AI models needed to predict the progression of both ALS and MS.

Finally, a subset of the data in the BRAINTEASER Semantic Data Cloud will be exported to the European Open Science Cloud (EOSC) and they will be also shared and exploited for the Open Evaluation Challenges.

Figure 2 shows an overall picture of the whole data flow associated with the BO and the BRAINTEASER Semantic Data Cloud, also in relation to Open Evaluation Challenges and the EOSC.

Data flow
Figure 2.The overall data flow associated with the BO and the BRAINTEASER Semantic Data Cloud.

In summary, the BO ontology will model the following data sources:

  • “Raw” data [anonymized]: these are the retrospective and prospective data discussed above:
    • Clinical data
    • Sensor/App data
  • Generated data: once trained on the above data, the AI models can be serialised as well and become part of the modelled data.
    • Serialized AI models
  • Evaluation Challenges: they will rely on three kinds of data which become part of the modelled data:
    • Evaluation Corpora: these are the training/validation/test sets and they are obtained by selecting an appropriate subset of the “raw” data;
    • AI models outputs: these are the results produced by the participating systems;
    • Performance scores and statistical analyses: the results produced by participants will be scored and then statistical analyses will be computed to assess them.

The BO will also allow to link these data with other resources available in the Linked Open Data Cloud.

The Brainteaser Ontology: Overview back to ToC

This ontology has the following classes and properties.

Classes

Object Properties

Data Properties

Annotation Properties

Named Individuals

2 Background

The remainder of this Section describes the background that underlies the Brainteaser ontology. Subsection 2.1 Describes the role of the ontologies, how they work and why they are so important especially in the medical domain. Subsection 2.2 Concerns RDF, the approaches actually used to define an ontology, and the serialization process. Subsections 2.3 and 2.4, on the other hand, details on the current state-of-the-art and related works. In particular, subsection 2.3 details which other efforts have been made to model the Multiple Sclerosis and the Amyotrophic Lateral Sclerosis. Furthermore, it will describe how the proposed ontology is capable of overcoming current limitations. Finally, section 2.4 contains a brief description of the main ontologies that have been exploited to build the Brainteaser ontology which grant to our ontology the required interoperability.

2.1 Ontologies

The Semantic Web is an extension of the World Wide Web based on standards set by the W3C [FHH+07]. At its basis, the Semantic Web is a form of network of interconnected data exploiting the Web. In particular, it provides a common framework that allows data to be shared and reused across applications, enterprises, and community boundaries.

While the original Web is mainly focused on the interchange of documents connected among them by link deprived of semantic, the aim of the Semantic Web is twofold: to go beyond the simple publication of documents by adding semantic to the links connecting them; and enabling computers to perform more useful tasks and support trusted interactions on the network [PMZ10]. In 2006 Tim Berners Lee coined the term Linked Data to indicate structured data interlinked with other data to become more useful through the use of query that exploit this presence of semantic on the edges [HB11]. Linked Data is based on a set of rules, outlined by Berners-Lee [BHBL11]:

  1. Use URIs (now IRIs) as names for things.
  2. Use HTTP URIs so that people can look up those names.
  3. When someone looks up a URI, provide useful information using standards such as RDF and SPARQL.
  4. Include links to other URIs, so that they can discover more things.

In this context, the world “ontology” has become extremely popular since the mid nineties as a construct containing information and definitions about concepts and the relationships among them [IB14]. In particular, in the domain of medicine, different resources are used alongside ontologies. These are controlled vocabularies, taxonomies, and thesauri [IB14].

A controlled vocabulary is a closed list of named subjects, which can be used for classifications. The constituents are called terms, i.e., names assigned to certain concepts. A taxonomy is an abstract structure that presents subject-based classifications that arrange terms from a controlled vocabulary into a hierarchy. The term thesaurus may refer to various subject classification structures that extend taxonomies allowing other statements about the subjects in the hierarchy. An example is the addition of associative relationships to the parent-child one.

Ontologies, more specifically, are computer science constructs [Kon15] that provide well-defined vocabularies which, in turn, allow precise and machine-readable description of knowledge about a certain domain [CJB99]. In computer science, one of the first definitions of ontology that we found is that of an “explicit, formal specification of a shared conceptualization” [Gru95].

Independently from the formal definition of the term, there are today many artifacts called ontology that provide a series of main features, used in almost all the applications based on them [HSG15]. These are:

  1. The definition of classes and relations through the use of identifiers such as the Internationalized Resource Identifier (IRI) to enable data integration across multiple databases.
  2. The definition of a domain vocabulary, a list of terms associated with classes and relations.
  3. Definitions, metadata, descriptions, and examples about classes and relations to allow domain experts to consistently understand their precise meaning.
  4. Formal definitions through the use of axioms that are considered true within the domain. In this way, background knowledge about the domain itself is provided. Reasoners can then use this information to unlock automated access to the meaning of classes and relations such as inference of new information from the data. Ontologies are used to respond to different needs: (1) to share a common understanding of the structure of information among people or software agents; (2) to enable the reuse of the domain knowledge; (3) to make domain assumptions explicit; (4) to separate domain knowledge from the operational knowledge; (5) to analyze the domain knowledge [NM01].

In the last decade they have been pervading almost all research domains [IB14], and, in particular, the biological and biomedical ones [HSG15], where multiple examples confirm their success [Kon15]. Ontologies are today often written using the Web Ontology Language (OWL) [GHM+08], a family of knowledge representation languages for authoring ontologies characterized by formal semantics and built upon the W3C Resource Description Framework (RDF) standard.

2.2 RDF, OWL, and Serialization Formats

RDF is a family of specifications for the publication of information on the Web endorsed by the W3C Consortium. In recent years, it has become the de-facto standard for the publication, access and sharing of data on the Web, since it allows for the flexible manipulation, enrichment, discovery and reuse of data across applications, enterprises, and communities [SMS+17].

In RDF, a resource is represented by an IRI, a Literal value or a blank node. An IRI (Internationalized Resource Identifier) is an extension of the URI (Uniform Resource Identifier) that can also contain UNICODE characters. A literal is a string representation of a certain value such as a string, a number or a date. It may be labeled with information such as the language or the datatype of the represented value. A blank node is a URI-like string which has validity only inside the considered database [PAG09].

One RDF statement is a triple composed of a subject, a predicate and an object. Subject and predicate are IRIs, while objects can also be literals. A literal, in particular, can only be an object. A blank node can either be a subject or an object. The combination of triples, where the object of a triple becomes the subject of another triple generates a directed graph, called RDF Graph.

OWL 2 is an ontology language for the Semantic Web with formally defined meaning. It is an extension and revision of the first OWL language, and it was published by the W3C Ontology Working Group in 2004. OWL 2 ontologies provide classes, properties, individuals, and data values stored in Semantic Web documents. It is intended to represent rich and complex knowledge about things, groups of things, and relations among them. Being a computational logic-based language, the knowledge expressed in OWL can be reasoned with by computer programs either to verify the consistency of that knowledge, or to make implicit knowledge explicit through inference. OWL documents, often referred simply as ontologies, can be published in the World Wide Web, and may refer to or be referred from other OWL ontologies. OWL is part of the W3C’s Semantic Web technology stack, which also includes RDF and SPARQL [HKP+09].

Today several serialization formats are available for RDF data. Among these, some of the most famous are N-Triples, Turtle, RDF/XML, and JSON-LD. We briefly describe each of these and report a small example describing the same concept “head” (uberon:000033) with a label, a comment, the specification of being an owl class and sub class of “Anatomical Structure” (uberon:000061).

  • N-Triple is arguably the simplest RDF format. It is a line based, plain text serialization format and subset of Turtle, easy for software to parse and generate. Each line of an N-Triple file has either the form of a comment (starting with the # symbol) or of a statement. A statement consists of four parts, separated by a whitespace. These four parts are the subject, the predicate, the object and a full stop, to indicate the end of the statement.

      <http://purl.obolibrary.org/obo/UBERON_0000033> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://www.w3.org/2002/07/owl#Class> .


      <http://purl.obolibrary.org/obo/UBERON_0000033> <http://www.w3.org/2000/01/rdf-schema#subClassOf> <http://purl.obolibrary.org/obo/UBERON_0000061> .


      <http://purl.obolibrary.org/obo/UBERON_0000033> <http://www.w3.org/2000/01/rdf-schema#comment> "The head is the anterior-most division of the body [GO]."@en .


      <http://purl.obolibrary.org/obo/UBERON_0000033> <http://www.w3.org/2000/01/rdf-schema#label> "head"@en ."

  • Terse RDF Triple Language (Turtle) is a common data format for storing RDF triples that differs from N-Triples in that it provides ways to abbreviate the information representation by factoring out, among other things, common portions of URIs. Among the features of the Turtle language, we count: the use of @base IRI and relative IRIs, @prefix and prefixed named, predicate lists separated by “;”, object lists separated by “,”, and the token a to represent the property rdfs:type.

     <http://purl.obolibrary.org/obo/UBERON_0000033> rdf:type owl:Class ;


                                         rdfs:subClassOf <http://purl.obolibrary.org/obo/UBERON_0000061> ;


                                         rdfs:comment "The head is the anterior-most division of the body [GO]."@en ;


                                         rdfs:label "head"@en .


  • RDF/XML is a serialization to express an RDF graph as an XML document. To do so, nodes and predicates are represented in XML terms: element names, attribute names, element contents and attribute values.

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000033">

               <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000061"/>

               <rdfs:comment xml:lang="en">The head is the anterior-most division of the body [GO].</rdfs:comment>

               <rdfs:label xml:lang="en">head</rdfs:label>

    </owl:Class>

  • JSON-LD is a serialization of RDF in Javascript Object Notation whose synthax is designed to easily integrate into deployed systems that already use JSON, It is primarily intended to be a way to use Linked Data in Web-based programming environments and to store Linked Data in JSON-based storage engines. It is 100% compatible with JSON and thus also with the JSON parsers and libraries available today.

    {

    "@id" : "http://purl.obolibrary.org/obo/UBERON_0000033",

    "@type" : [ "http://www.w3.org/2002/07/owl#Class" ],

    "http://www.w3.org/2000/01/rdf-schema#comment" : [ {

    "@language" : "en",

    "@value" : "The head is the anterior-most division of the body [GO]."

    } ],

    "http://www.w3.org/2000/01/rdf-schema#label" : [ {

    "@language" : "en",

    "@value" : "head"

    } ],

    "http://www.w3.org/2000/01/rdf-schema#subClassOf" : [ {

    "@id" : "http://purl.obolibrary.org/obo/UBERON_0000061"

    } ] }

2.3 Existing Ontologies for ALS and MS

Some previous effort has been devoted to developing and exploiting ontologies related to ALS and MS. The largest part of the work has been dedicated to model Multiple sclerosis [JCS+13, JCR+14, MGR+15, DLT+19, AAA+20], or related concepts such as the EDSS [GSS+05, GSS+09], potential lesions [DE06, GFB+14], or relapses [PRP2020], and use them to predict the progression of the disease [PRP2020]. With respect to ALS, the most relevant works are about the modeling of the care pathway and service provision to patients affected by ALS [CMA+18, CMA+21]. Finally, a line of work investigates the possibility of jointly modeling several diseases, either neurodegenerative [HCD08, CJD+12, JCC+13, GMR+19] or rare [SCA+20] ones - among which authors include ALS and MS. Compared to ALS, MS has received far more attention by the research community for what concerns its modeling through ontologies. We report here the major accomplishments made in this regard. In [JCR+14] Jensen et al. developed the Multiple Sclerosis Patient Data Ontology (MSPD) to represent data from patients affected by MS in the New York State Area. Although very similar to our objective, at the time of writing the ontology is not publicly available and does not include any pieces of information about the ALS. The Multiple Sclerosis Ontology (MSO) [MGR+15] is one of the most comprehensive efforts made in order to model the MS using an ontology. The MSO is validated in the task of automatically annotating Electronic Medical Records and it is capable of achieving an adequate performance of 73% of F1 score. More recently, Alshamrani et al. in [AAA+20], even though not directly involved in the creation of an ontology, present a global overview of the efforts made to utilize ontologies to favour model-driven decision making in multiple sclerosis research. Several works do not model the MS in its entirety, but only some aspects of it. Our work, on the other hand, proposes a holistic approach to model Multiple Sclerosis. For the sake of completeness, we report the main works that model minor aspects of the MS. In [GSS+05] and later in [GSS+09], Gaspari et al. explore the possibility to compute the automatic EDSS (called AEDSS) exploiting an underlying ontology. They identify four main ontological classes: the rules used to infer the EDSS scores, the anatomical functional systems associated with each rule, the questions that allow to assess the degree of impairment, and the overall score. The ontology is therefore used to improve the performance of an expert system. [DE06], on the other hand, exploits an ontology to define rules that can be applied on the automatic categorization of images, to individuate lesions on the brain due to MS. Finally, Pappalardo et al [PRP2020] modelled the Universal Immune System Simulator (UISS), an ontology that describes the immune system activities. The authors also extend the UISS to simulate underlying MS pathogenesis and its interaction with the host immune system. Efforts have been made to ontologically model the care of patients affected by ALS [CMA+18, CMA+21]. Even though the ontologies developed are rich and detailed, they model aspects which are not directly involved in our project. In particular, the focus of both work is on the quality of life and care pathway of patients affected by ALS. Some efforts have been devoted to model multiple neurological diseases with the intent of obtaining a general ontology. An example is the Neurological Disease Ontology (NDO) [CJD+12, JCC+13]. According to The authors, NDO can provide a set of classes to describe the neurological diseases, their symptoms and possible interventions encountered during the clinical practice. Based on such effort, in [JCS+13] Jensen et al. try to adapt the NDO to the modeling of Multiple Sclerosis. Notice that, similarly to MSPD, at current time the NDO does not respect the FAIR principles, since it is neither Findable nor Accessible, thus also preventing Reusability. In [SCA+20] Subirats et al. aim at modeling several rare diseases, including multiple sclerosis, through an ontology, dubbed Holistic Rare Diseases Ontology (HORD). In such ontology it is possible to model also information derived from the patients’ social networks, in order to maintain unstructured data that can be used to assess their current state.

2.4 Ontologies Used in the BRAINTEASER Ontology

The use of standard identifiers for classes and relations is a key component when creating ontologies to ensure data integration across multiple disconnected databases, files or web sites. The ability to use parts of ontologies to generate new ones specifically tailored for some new application or context while, at the same time, maintaining interoperability with other datasets, is essential [HSG15]. When more ontologies are used in the process of searching for already defined entities and relations, ontology repositories can aid in finding ontologies suitable for annotating data within a specific domain. Among the main resources in the life science domain, we primarily used OntoBee [XMRH11], an ontology repository in which ontologies are presented as Linked Data.

Table 1: Table describing the main ontologies that the brainteaser ontology exploits. For each ontology, we report the prefix that is used throughout the description of the Brainteaser ontology, the URL associated with the prefix and the name of the ontology.
prefix url ontology
https://www.brainteaser.health/ontology/schema/ Brainteaser ontology (base prefix)
foaf http://xmlns.com/foaf/spec/ Friend of a Friend (FOAF) vocabulary
ncit http://purl.obolibrary.org/obo/NCIT_ National Cancer Institute thesaurus (NCIT)
ogg http://purl.obolibrary.org/obo/OGG_ Ontology of Genes and Genomes (OGG)
oboInOwl http://www.geneontology.org/formats/oboInOwl# OBO in OWL
uberon http://purl.obolibrary.org/obo/UBERON_ Uberon
xsd http://www.w3.org/2001/XMLSchema# XML Schema
maxo http://purl.obolibrary.org/obo/MAXO_ Medical Action Ontology (MAxO)
omit http://purl.obolibrary.org/obo/OMIT_ Ontology for MIRNA Target (OMIT)
snomed http://purl.bioontology.org/ontology/SNOMEDCT/ SNOMED Clinical Terms (SNOMED CT)
atcc http://purl.bioontology.org/ontology/UATC Anatomical Therapeutic Chemical Classification (ATCC)
umls https://uts.nlm/nih.gov/uts/umls/concepts Unified Medical Language System
isco http://data.europa.eu/esco/isco/ International Standard Classification of Occupations
efo http://www.ebi.ac.uk/efo/EFO_ Experimental Factor Ontology

The ontologies used in this project are presented, together with the respective prefixes, in Table 1 . Among these ontologies, some of the most important ones are:

  • FOAF (Friend of a Friend) [GCB+07]: an ontology describing people, their activities and their relations to other people and objects.
  • The NCI (National Cancer Institute) Thesaurus OBO Edition [KS05]: a reference terminology that includes broad coverage of the cancer domain, containing cancer related diseases, fundings and abnormalities.
  • XSD (XML Schema Definition): a recommendation of the World Wide Web Consortium, specifies how to formally describe the elements in an XML document. It presents, in particular, the definition of many data types also used in RDF.
  • OGG (Ontology of Genes and Genomes) [HLZ14]: The Ontology of Genes and Genomes is a well-known ontology used to model Genes, their mutations and the genome of living organisms.
  • MAXO (Medical Action Ontology) [CZV+19]: This Ontology provides classes to describe the majority of the procedures that can be carried out by medical doctors while visiting or treating the patients.
  • OMIT (Ontology for MIRNA Target) [HTD+10]: The MiRNA Target Ontology is a well-known ontology meant to develop data exchange standards in the microRNA domain. Although we do model directly aspects related to the microRNA, being a comprehensive ontology, we exploit it to import support classes.
  • ATCC (Anatomical Therapeutic Chemical Classification): The ATCC Ontology associates each ATC code with the corresponding active substance. It is used to model the pharmacological prescription assigned to the patients. The ontology has substantially a class for each active substance.
  • Uberon: an anatomical ontology that represents body parts, organs and tissues in a variety of animal species, with a focus on vertebrates.
  • SNOMED CT: SNOMED Clinical Terms is a systematically organized and computer processable collection of medical terms providing codes, terms, synonyms and definitions used in clinical documentation and reporting. It is considered one of the most comprehensive multilingual clinical healthcare terminology in the world.
  • Unified Medical Language System (UMLS): is a set of files and software that brings together many health and biomedical vocabularies and standards to enable interoperability between computer systems. It integrates and distributes key terminology, classification and coding standards, and associated resources to promote creation of more effective and interoperable biomedical information systems and services, including electronic health records. In particular we exploited the UMLS Metathesaurus, a large biomedical thesaurus, the biggest component of UMLS, that is organized by concept, or meaning. It links synonymous names from over 200 different source vocabularies.

In BO we also use the International Classification of Diseases, in its tenth edition (ICD-10). This is a healthcare classification system that allows more than 55.000 different codes and permits tracking of many new diagnoses and procedures. It is maintained by the World Health Organization (WHO). Also, we use the International Classification of Primary Care (ICPC) ontology, containing the OWL version of the ICPC classification method, that allows for the classification of the patient’s reason for encounter, the problem and diagnosis being managed, the primary or general health care interventions, and the ordering of the data of the primary care session in an episode of care structure

3 Co-Design Approach

To design the BO ontology we adopted a co-design approach, strictly collaborating with the medical partners and domain experts, in order to embed their knowledge in the BO and, at the same time, to validate all the design choices. To this end, we operated in an iterative way, producing several intermediate versions of the ontology and discussing them with our domain experts.

The design of the BO started by discussing with all the partners which kind of data have to be managed via the ontology and this ended-up on identifying the three categories mentioned above in Section 1: “raw” data, generated data, and evaluation campaigns data. The discussion was initiated during the kickoff meeting in January 2021 and finalized in the first plenary meeting in April 2021.

At this point, the work specifically focusing on retrospective data started. The UNIPD team received simplified samples of data from the medical partners in order to start understanding their features and potential issues. We then prepared forms to elicit requirements from the medical partners and collect attributes that they deemed important to describe both ALS and MS.

The requirement gathering and analysis phase ended up with a preliminary draft of the core parts of the BO and the corresponding schema. This preliminary draft of the BO was discussed face-to-face (virtually) in a dedicated meeting with medical partners in late May 2021, where we went through the overall design choices and the specific classes constituting the BO to validate them. The further feedback gathered from the domain experts led to a revision of the BO which was further discussed in another face-to-face virtual meeting in late June 2021. This additional feedback led to a further refinement of the BO which was then presented and agreed on during the overall plenary meeting in September 2021.

Just after the plenary meeting, full (and anonymized) retrospective data were received from the medical partners: Pavia for MS; Lisbon, Turin and Madrid for ALS. The inspection of the full raw data allowed to further improve and refine the ontology and also to discover some issues about the instances, related to incomplete or noisy data. These updates to the BO and the solutions to address specific issues have been then discussed in one-to-one meetings with the specific medical partner during October and November 2021.

Overall, all these iterations led to the development of the first version of the BRAINTEASER ontology as well as of the mappers for ingesting the retrospective data from the medical partners.

4. DESCRIPTION OF THE BRAINTEASER ONTOLOGY

In the following, we describe more in detail the ontology designed to model the Multiple Sclerosis and the Lateral Amyotrophic Sclerosis according to the co-design approach defined in Section 3. In this section we present the main components and the choices that we made, whereas the complete documentation will be uploaded with the final OWL file in an open public repository as Zenodo which enables the seamless integration with EOSC services. Subsection 4.1 details the principles that guided the development of the ontology, while Subsection 4.2 describes the main semantic areas and the principal classes available in each of them.

4.1 Overall design principles

The ontological modeling proceeded bottom-up starting from the anonymized clinical reports about the four considered diseases provided by the "Instituto de medicina molecular Joao Lobo Antunes" (iMM, Portugal) and Università degli Studi di Torino (UNITO, Italy) for ALS, and by Fondazione Istituto Neurologico Nazionale Casimiro Mondino (MNDV-PV, Italy) for MS.

We analyzed these records and worked together with the physicians and the expert researcher in the field, following shared co-design principles, to accurately identify the classes and relations to include in the ontology. We maximized the re-use of concepts defined in already available and well-known ontologies and vocabularies, thus limiting the creation of new classes and relations to a minimum.

We represent the ontology as a graph where nodes are classes and edges are typed relationships amongst the classes. Classes (nodes) represent real-world objects such as a person, a project, a tissue or an anatomical part.

Relationships (edges) describe how the classes interact one with each other. BO is composed of 362 classes, 360 named individuals, 76 object properties, 220 data properties, and EEE annotation properties. The prefixes used in the ontologies are reported in the table above. Amongst the most used external ontologies, we count the COMPLETE with statistics.

Once released, the URLs of the ontology will be secure and permanent by using the re-direction service provided by the W3 Permanent Identifier Community Group. The service works as a switchboard connecting requests for information with the true location of the information on the Web. It can be, therefore, reconfigured to point to a new location if the old location stops working.

4.1 Overall design principles

The ontology is divided into eight "semantic areas", i.e., groups of entities and relationships that pertain to different types of concepts and aspects of our domain. Each entity is therefore classified in one of the eight semantic areas. These areas are better detailed in section 4.2, and are:

  1. Patient the semantic area describing aspects of the patient, such as their status, their relatives, the corresponding disease, and clinical trials to which they are participating.
  2. Genetic Data the information about the genetic mutations of a patient.
  3. Behavior containing entities about the behaviour kept by the patient through time, such as smoking, physical activity, and more generic lifestyle aspects.
  4. Events classes describing the possible events being registered for a patient, such as diagnosis, onset, and interventions of different nature.
  5. Contingencies an area containing classes describing things that can happen to the patient during their life, such as comorbidities and traumas of different kinds.
  6. Intervention and Procedure containing classes about different types of procedures that the patient may incur during their clinical history. This is one of the largest areas of the ontology, and we divided it into sub-areas to better describe them depending on the nature of the procedure.
  7. Anatomical Structure composed of subclasses describing different parts of the human body.
  8. Symptoms subclasses describing symptoms of different nature that may happen to the patients.

4.1.2 External Ontologies and Taxonomies

Whenever possible, we re-used classes from other ontologies to represent entities and created new classes only when unavoidable. The external ontologies used for this are described in Section 2.4.

In particular, there are some cases where we imported a subset of entities from an external ontology in order to represent taxonomies of concepts and their rdfs:subClassOf relationships. We only imported from these taxonomies the classes that are useful to model the data necessary for the project, i.e. we never import the full taxonomies, but only subsets of them. Some of the classes that work as roots of their respective taxonomies in the Brainteaser ontology are:

  1. Relative (ncit:C21480) This class represents a generic relative of a patient, and is the root of the taxonomy containing different degrees of kinship (such as Father, Mather, Sister, etc.)
  2. Occupation (esco:Occupation) The class representing a generic job or other type of occupation of the patient.
  3. Ethnic group (SNOMED:Ethnic_group) Represents the ethnicity of the patient.
  4. Symptom (ncit:C4876) The root class of the taxonomy describing the possible symptoms related to a patient.
  5. Gene (ogg:0000000002) Root of the gene taxonomy.
  6. Anatomical Structure (uberon:0000061) Root of the taxonomy of the human body locations where events, symptoms and traumas are located.
  7. Pharmacologic Substance (ncit:C1909) the root of the clinical drugs that may be prescribed to patients as result of a Therapeutic Procedure or as response to a Relapse or Inflammation.
  8. Disease or Disorder (ncit:C2991) the root of the taxonomy with the possible diseases (not only MS and ALS) that a patient, or one of their relatives, may manyfest.

We relate each single concept in the BO with the respective concepts in the Unified Medical Language System (UMLS) metathesaurus with the oboInOwl:equivalentClass relationship. This connection allows us to retrieve all relevant information about a concept as reported in the rich and widely-used UMLS meta-thesaurus. UMLS comprehends alternative naming for the concepts, relationships with other relevant classification schemes such as the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) and multilingual information when available.

As an example, the "multiple sclerosis" concept is inherited from the MONDO ontology with URI http://purl.obolibrary.org/obo/MONDO_0005301 and in the BO definition for this concept we also report that it is the same as umls:C0026769. From the UMLS identifier we can retrieve all the information about other classifications such as ICD-10 that identifies multiple sclerosis with the id G35.

4.1.3 Named Individuals

For the classes contained in some of these taxonomies, i.e., the ones with root in Occupation, Ethnic Group, Anatomical Structure, and Pharmacological Substance, it is the case that, when they are the range of properties, no other information needs to be registered. For instance, when registering the presence of a symptom in a particular anatomical location, it is only necessary to know the location, without any further information about it.

The consequence is that each time a new triple with an object in one of these taxonomies is created, we would be forced to create a new instance.

To avoid an explosion in the number of instances of these classes, and due to the fact that no other information about them needs to be modeled, we decided to create named individuals, one for each class in these taxonomies. These named individuals are used as objects of the corresponding object properties every time a new triple needs to be instantiated.

4.2 Area-by-Area

In the remainder of this section, we describe the elements characterizing each semantic area individuated in section 4.1. We use the bold font to indicate ontological classes, monospace font to represent their URI and italic to represent their properties. In case of uri derived from other ontologies, prefixes are defined in Table 1.

4.2.1 Patient

The patient semantic area, represented in Figure 3, contains classes and relations pertaining to a patient participating in the clinical trials and general information about this patient, their relatives with diseases, their disease and the participation in a clinical trial.

Central to this area is the Patient class (ncit:C16960), subclass of foaf:Person, that presents different properties describing the Patient instance. These are: dateOfDeath (with range xsd:gYear), genomeSequencing (xsd:string), educationLevel (rdf:langString), maritalStatus (rdf:langString), dextricity (xsd:string), retiredAtDiagnosis (xsd:string), menopause (xsd:int), MSInPaediatricAge (xsd:boolean), alive (xsd:boolean).

Patient inherits from foaf:Person the properties birthplaceCharacteristics (rural or urban areas), and birthplace (defined as an enumeration among village, country town, small town, middle torn, and large town). The Patient is further linked to two additional attributes, gender through the foaf:gender property, and birthday, via foaf:birthday property. In order to preserve the anonymity of the patients, real instances will only present the birth year, and not the birth date.

Patient is connected through the ethnicity property to class Ethnic Group (SNOMEDCT:Ethnic_Group), representing a generic ethnic group. This class is the root of a taxonomy of ethnicities whose classes are taken from other ontologies.

To model the familial predisposition, it is necessary to register the presence of a patient's relatives that may have the studied diseases of their own. To do so, we considered the class Relative (ncit:C21480) that models a generic relative of a patient. Relative, in turn, is the root class of a taxonomy of kingship classifications such as Parent, FirstDegreeRelative, Father and Mother (these classes are imported directly from the ncit ontology).

A relative may or may not be a patient in the database. In the first case, the relative instance is connected to its corresponding patient instance through the isPerson property. In the other case, an instance of the class foaf:Person is created, and the relative instance is connected through isPerson to this instance. One patient or one generic person can be a relative of more than one patient, and for this reason multiple instances of relative may be instantiated, one for each degree of kinship occurring for that patient/person in the database. Each of these instances will be connected through isPerson to the corresponding instance of Patient or foaf:Person.

BRAINTEASER: patient area

Figure 3. Patient semantic area, including the classes Patient, Person, Relative, Clinical Trial, Clinical Trial Participation, and Disease or Disorder.

The class Occupation (ESCO:Occupation) represents the job of the user. It is the root class of a taxonomy of classes representing different types of jobs, and a patient instance is connected to Occupation through hasOccupation.

foaf:Person is connected through the property enrolledIn to Clinical Trial Participation (:ClinicalTrialParticipation), representing the fact that a patient is participating in a clinical trial. A clinical trial instance may have a startDate property, an endDate property and an ending reason, provided by the endReason property.

Each instance of clinical trial participation is part of a Clinical Trial (ncit:C71104) and connected to this class through the participate property. In turn, a clinical trial pertains to a certain hospital, and therefore the property connects the class Clinical Trial to the class Clinics and Hospitals (ncit:C19326).

Finally, a person (thus both a patient and a relative who is not present in a trial) can have a disease. foaf:Person is connected to Disease or Disorder (ncit:C2991) through hasDisease. Also, the class Clinical Trial is connected to Disease or Disorder through isAboutDisease to indicate which is the disease studied in the specific trial.

4.2.2 Genetic Data

BRAINTEASER: gene area

Figure 4. Semantic Area containing the information about a patient's gene and their mutations.

A Patient may be associated with data concerning their genetic heritage. To do so, the ontology links the Patient, via the property hasGene, to the class Gene (ogg:0000000002), as shown in Figure 4. Instances of this class can have two properties: kind and open box. The former allows to express the type of mutation present on the gene, while the latter allows to add further information via unstructured text. The Gene instance can be instantiated either using the Gene class, or one of its relevant subclasses for this specific domain: SOD1 (ogg:3000006647), FUS (ogg:3000002521), C9orf72 (ogg:3000203228), and tardbp (ogg:3000023435).

4.2.3 Behaviour

BRAINTEASER: behavior area

Figure 5. Behaviour and Lifestyle semantic area, including the subclasses Smoking, Physical Activity and Lifestyle.

Different aspects of the behaviour of the patient during the passing of time are modeled with classes in this semantic area.

As reported in Figure 5, the main class is Behaviour (ncit:C19683), presenting the properties startYear and endYear (both with range xsd:gYear), describing the starting and ending dates of said behaviour. Each instance of the subclasses of Behaviour therefore offers the possibility to register the time span in which such behaviour was sustained. The class Event is connected to Behaviour through hasRegisteredBehaviour.

Different types of behaviours are modeled through the use of subclasses of this main class.

Smoking (ncit:C154329) represents the patient's habit of smoking. It presents the relations packYear (a quantification of lifetime tobacco exposure defined as: (number of cigarettes smoked per day) x (number of years smoked)/20. Thus, one pack-year corresponds to smoking 20 cigarettes a day for one year), and dailyCigarettes (the number of cigarettes smoked in one day on average).

The class Physical Activity (ncit:C17708) describes the physical activity usually exerted by the patient. Its properties are intensity (xsd:string), weeklyFrequence (xsd:integer) and activityType (xsd:string).

The class Lifestyle (ncit:C16795) acts as a container where to put different types of behavioral information concerning the patient. Such behaviors are modeled as properties of the Lifestyle instance, and are: sunExposure (with range xsd:int), diet (xsd:int), fatigue (xsd:int), sexuality (rdf:langString), femalePeriodStartDate (xsd:date), and menopause (xsd:boolean).

4.2.4 Events

BRAINTEASER: event area

Figure 6. Events Semantic Area, including the class Event and its subclasses: Protocol Event, Diagnosis, Before Onset and Onset.

This Events semantic area, depicted in Figure 6, contains some of the most important classes of the ontology, as one of the goals of the ontology itself is to model the events pertaining to the patient and their evolution through time.

Main class here is Event (ncit:C25499), describing a generic event that can happen to a patient in a medical environment. The Event class is characterized by the two data properties endDate and startDate (both with range xsd:date), describing the period in which this Event manifested.

Different types of Event are represented through the use of subclasses.

Protocol Event (ncit:C74589) represents a planned protocol activity such as randomization and study completion, and occurrences, conditions, or incidents independent of planned study evaluations occurring during the trial (e.g., adverse events) or prior to the trial (e.g., medical history). Its subclass is Patient Visit (ncit:C39564), describing a specific type of protocol event, i.e., a visit of the patient in a hospital.

The event Diagnosis (ncit:C25279) represents the moment in which the patient is officially diagnosed with the disease.

The last two types of Event are the Onset (ncit:C25279) and Before Onset (:BeforeOnset). The first one represents the event in which the first symptoms are manifested for the first time to the patient. The Onset, in particular, may be of different types, which are represented as boolean (xsd:boolean) properties: limbs, bulbar, axial, and generalized. An onset may also present the property cerebrospinalOligloconalBands, which indicates, if the test has been carried out, the presence of such bands in the patient's blood flow. The onset is located in a part of the human body, and thus the Onset event is connected to the class Anatomical Structure (uberon:0000061) through the site property. The second one, Before Onset, describes an event that happened before the onset, whatever its nature may be. The property howLong registers how much time before the onset this event happened, and it may assume only two string values, defining an event that happened in the last five years, or before the last five years.

An Event instance, in turn, may be linked to various other classes. Event is linked through hasPregnancy to Pregnancy, describing the presence of a pregnancy; to Trauma through hasTrauma, describing the registration of a traumatic event happened to the patient; to Symptom through hasSymptom, describing the presence of symptoms being registered during an event, to Recurrent Disease through hasRelapse, and finally to one or more Intervention or Procedure that may be applied to the patient, through the consist property.

4.2.5 Contingencies

The Contingencies semantic area, represented in Figure 7, contains classes representing "things that may happen": occurrences to the patient that may or may not be related to the disease. They correspond to phenomena in the patient body that cannot be directly planned. We also included a pregnancy among contingencies since, even though partially plannable, it represents a change in the patient body that cannot be ascribed among the medical procedures. These contingencies are still registered during an Event and therefore are linked to the Event in which they are registered via a specific property each.

BRAINTEASER: contingencies area

Figure 7. Contingencies semantic area, composed of classes Recurrent Disease, Trauma, Pregnancy, and Comorbidity.

The classes in this section are:

  • Trauma (ncit:C3671), that describes the presence of a trauma to the body of the patient. It also reports the properties traumaDate (xsd:date) and traumaDescription (rdf:langString). The Trauma class is connected to the Anatomical Structure class through the traumaArea object property. It is furthermore linked to the Event during which it is registered via the hasMajorTrauma property.
  • Pregnancy (ncit:C25742) describes the presence of a pregnancy. Event is connected to this class through the hasPregnancy property. This class presents a series of properties about the pregnancy itself: startDate and endDate (xsd:date), endEvent (rdf:langString, it describes how the pregnancy ended), complications (rdf:langString).
  • Recurrent Disease (Relapse) (ncit:C38155) describes a relapse that may happen to the patient. This class has, in turn, a series of properties describing the relapse, such as relapseStartDate, sequela, recovery, length, etc. The Event object is connected to the Relapse class through the hasRelapse property. Relapse, in turn, may be associated to a Pregnancy (hasAssociatedPregnancy), to a prescribed Pharmacologic Substance (associatedSubstance), to a requested MRI (requiresMRI), and to a possible Intervention (relapseAssessment) required to assess the presence of the relapse itself.
  • Comorbidity (ncit:C16457) represents the presence of two or more diseases or medical conditions in a patient. The Comorbidity is characterized by the startYear and endYear property, together with treatment (xsd:string), reporting the prescribed treatment, and severity, describing the severity of the comorbidity from a set of string values (slight, moderate, serious, life risk). A Comorbidity is registered during an Event, and the two classes are connected through hasRegisteredComorbidity.

4.2.6 Intervention and Procedure

This semantic area contains the classes describing the interventions done to a patient to understand, keep under control, and intervene on their clinical condition.

The class Event is connected to the main class of this area, Intervention or Procedure (ncit:C25218), through the consists object property. This class represents "a general activity that produces an effect, is meant to clinically assess, or is intended to alter the course of a disease in a patient" (from its NCI Thesaurus definition).

Instances of the Intervention or Procedure class can have two properties: startDate and endDate. Such dates allow us to register the starting and ending moment of the intervention, if this is something continued in time. Notice that, thanks to an abuse of notation, by leaving empty the endDate, we can also represent interventions and procedures that are atomic in time, i.e., are not distributed through more days. The ontology contains different subclasses for Intervention, and each of them supersedes a semantic sub-area depending on the nature of the procedure itself. We describe the characteristics of the main intervention and procedures in the remainder of this subsection.

4.2.6.1 Therapeutic Procedure
BRAINTEASER: therapeutic area

Figure 8. Therapeutic Procedure semantic area, sub-area of the Intervention or Procedure area.

The subclass Therapeutic Procedure (ncit:C49236), depicted in Figure 8, represents the action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process.

We considered three possible types of therapeutic procedures: a generic therapy (the Therapeutic Procedure class itself), a Disease Modifying Therapy (DMT) and a Mechanical Ventilation (NIV) (ncit:C171457).

DMT presents the property seriousAdversarialEvent (also referred to in the documents as SAE), which indicates the occurrence of a serious adverse reaction to a specific Disease modifying therapy.

All the possible therapeutic procedures might involve the prescription or the associated usage of one or more pharmacological substances. The administration of these substances is modeled here through the use of the class Administration (ncit:C25409), characterized by properties describing the administration itself: administrationRoute (rdf:langString), endReason (rdf:langString), dose (xsd:float), medicineName (xsd:string), frequency (rdf:langString).

An Administration is related to the administered substance, here represented through the class Pharmacological Substance (ncit:C1909), through the object property isRelated.

Among the possible substances that may be administered (subclasses of Pharmacological Substance), the following have been identified as particularly relevant to the domain: Vaccine (ncit:C923), Agent Affecting Nervous System (ncit:C78927) (and especially its subclass Riluzole (ncit:C47704)), and cortisone treatment (:cortisone_treatment).

4.2.6.2 Diagnostic Procedure
BRAINTEASER: diagnostic procedure area (part 1)

Figure 9.a. Part 1 of the Diagnostic Procedure semantic area, a sub-area of the Intervention or Procedure area. This figure reports the subclasses Pulmonary Function Test, Blood Test and EDSS.

Diagnostic Procedure (ncit:C18020) is another subclass of Intervention or Procedure, and it represents any procedure or test to diagnose and assess the progression of a disease or disorder. This, in turn, presents many subclasses. Due to this, we further divided the graphical representation of this sub-area in different Figures: Figure 9.a, 9.b and 9.c, to help their readability.

Starting from Figure 9.a, we see the Pulmonary Function Test (ncit:C38081). As the name suggests, it is used to store information about pulmonary function tests carried out on the patient. Instances of such class have several properties associated, each of which correspond to a parameter used to assess the quality of the respiratory functions of the patient (i.e., VC, FVC, etc. …). Another subclass here is the Blood Test (ncit:C49286), representing a test to measure hematopoietic components and investigate hematologic disorders. The relevant parameters assessed via a blood test are represented through the use of properties of this class.

The Expanded Disability Status Scale (EDSS) (ncit:C98302) is a subclass describing a system for quantifying the level of disability for multiple sclerosis. The EDSS is traditionally computed considering 12 different items: each of these items is represented by a property of this class with range xsd:float.

BRAINTEASER: diagnostic procedure area (part 2)

Figure 9.b. Part 2 of the Diagnostic Procedure semantic area, a sub-area of the Intervention or Procedure area. This figure reports the subclasses Questionnaire and clinical assessment.

We continue with the classes belonging to this sub-area in Figure 9.b. The Questionnaire (ncit:C17048) class represents a questionnaire that is submitted to the patients at each visit. In turn, different types of questionnaires may be submitted, with different sets of questions.

The class Clinical Assessment (maxo:0000487) represents a measurement performed in a clinical setting using clinicians' observations and instrument data to inform patient care and research. The instances of this class may contain different fields with the data collected during the assessment itself, as can be seen in the figure.

BRAINTEASER: diagnostic procedure area (part 3)

Figure 9.c. Part 3 of the Diagnostic Procedure semantic area, a sub-area of the Intervention or Procedure area. This figure reports the subclasses Evoked Potentials and Diagnostic Imaging, together with the properties connecting them to other classes of the ontology belonging to different semantic areas.

Finally, Figure 9.c reports the last classes of this sub-area. With Evoked Potentials (omit:0006295) we mean a class of tests used to measure the electrical activity in certain areas of the brain and spinal cord. Evoked potentials test and record how quickly and completely the nerve signals reach the brain. These types of tests are helpful in diagnosing such conditions as multiple sclerosis and other neurological disorders. Key properties for this type of Procedures are the potentialValue (a value among normal and altered), and the location. Electrical activity is produced by stimulation of specific sensory nerve pathways. In the ontology there are subclasses describing the different types of Evoked Potentials: Visual Evoked Potentials (omit:0006298), Motor Evoked Potentials (omit:0019166), Auditory Evoked Potentials (omit:0006296) and the Somatosensory Evoked Potential (omit:0006297).

With Diagnostic Imaging (ncit:C16502) we refer to various techniques of viewing the inside of the body to help figure out the cause of an illness or injury, and thus confirm a diagnosis. Doctors also use it to see how well a patient's body is responding to treatment for a fracture or illness. Subclasses of Diagnostic Imaging are the Magnetic Resonance Imaging, also known as MRI (ncit:C16809), characterized by properties describing its results, and the Positron Emission Tomography, also known as PET (ncit:C17007).

4.2.6.3 Surgical Procedure
BRAINTEASER: surgical procedure area

Figure 10. Surgical Procedure semantic area, sub are of the Intervention or Procedure area.

The Surgical Procedure class describes a generic surgical operation performed on the patient. As seen in Figure 10, Its subclasses represented in the ontology are: Percutaneous Endoscopic Gastrostomy (PEG, ncit:C10604), a procedure in which a flexible feeding tube is placed through the abdominal wall and into the stomach, allowing nutritions, fluids and medications to be put directly into the stomach, thus bypassing mouth and esophagus; tracheotomy (or tracheostomy, ncit:C15341), an opening surgically created through the neck into the trachea to allow direct access to the breathing tube; Cerebrospinal fluid examination (CSF Analysis, ncit:C173272), the analysis of the cerebrospinal fluid, a clear, colorless liquid found the the brain and spinal cord, acting like a cushion against sudden impact or injury to the brain or spinal cord. This last class is characterized by the properties cerebrospinalFluid and lymphocytes, describing aspects of the test's results.

4.2.7 Anatomical Structure

This area, shown in Figure 11, contains the Anatomical Structure (uberon:0000061) class. Such class, due to its nature and function, cannot be assimilated to any other already available classes and semantic areas.

The class Anatomical Structure is the root of a taxonomy containing classes representing parts of the human anatomy used throughout the ontology. To avoid creating new instances of a certain location every time it is required, we define a named individual for each of the required anatomical structures: all the resources that need to be associated with one or more anatomical structures will point to the same name individual.

The Anatomical Structure is the range of many object properties in the Brainteaser ontology. Some examples are site (connecting the Onset to the Anatomical Location), traumaArea (connecting the class Trauma and indicating where it happened), area (connecting the class Diagnostic Imaging), surgicalArea (connecting Anatomical Structure to the class Surgical Procedure), and symptomArea (connecting it to the class Symptom).

BRAINTEASER: anatomical structure area

Figure 11. Anatomical Structure Semantic Area

4.2.8 Symptoms

The Symptoms semantic area, shown in Figure 12, contains classes describing the symptoms that may happen to a patient and be registered during an Event.

The class Event is connected to the main class of this area, Symptom (ncit:C4876), through the hasSymptom object property. The Symptom class, in turn, is connected to the Anatomical Structure class through the symptomArea property, allowing to specify the area associated with a specific symptom.

The resources will be rarely of type Symptom, since it is too generic to describe any real characteristic of the patient's disease course. Among symptom instances, we list here the Nervous System Finding (ncit:C36280) and its subclass, the Fasciculation (ncit:C34606) and the Inflammation (ncit:C3137). These symptoms are among the most relevant concerning the diseases modeled in this ontology. For the case of Inflammation, in particular, we register the Pharmacologic Substance being administered, through the associatedSubstance object property.

BRAINTEASER: symptoms area

Figure 12. Symptoms semantic area.

Cross reference for The Brainteaser Ontology classes, properties and dataproperties back to ToC

This section provides details for each class and property defined by The Brainteaser Ontology.

Classes

A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways. [Definition Source: NCI]c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C28397

has super-classes
Disease or Disorder c
has members
asthma ni

abdominal fasciac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0013493

Abdominal fascia refers to the various types of fascia found in the abdominal region.
has super-classes
anatomical structure c
has members
abdominal fascia ni

Abdominal Painc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26682

has super-classes
Disease or Disorder c
has members
Abdominal Pain ni
is also defined as
named individual

acetylcarnitinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06BX12

has super-classes
Pharmacologic Substance c
has members
acetylcarnitine ni

aciclovirc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/J05AB01

has super-classes
Pharmacologic Substance c
has members
j05 a b01 ni

Acute Myocardial Infarctionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35204

has super-classes
Disease or Disorder c
has members
Acute Myocardial Infarction ni
is also defined as
named individual

Adenocarcinomac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2852

has super-classes
Disease or Disorder c
has members
Adenocarcinoma ni
is also defined as
named individual

Administrative and commercial managersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C12

Administrative and commercial managers plan, organize, direct, control and coordinate the financial, administrative, human resource, policy, planning, research and development, advertising, public relations, and sales and marketing activities of enterprises and organizations, or of enterprises that provide such services to other enterprises and organizations. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level Tasks performed by workers in this sub-major group usually include: formulating and administering policy advice and strategic and financial planning; establishing and directing operational and administrative procedures; implementing, monitoring and evaluating strategies and policies; providing advice to senior managers; directing the development of initiatives for new products, marketing, public relations and advertising campaigns; determining and directing sales activities, product mix and customer service standards; setting prices and credit arrangements; ensuring compliance with relevant legislation, regulations and standards; controlling selection, training and performance of staff; preparing budgets and overseeing financial operations; consulting with the chief executive and with managers of other departments or sections; controlling expenditure and ensuring the efficient use of resources; representing the enterprise or organization in negotiations, and at conventions, seminars, public hearings and forums. Occupations in this sub-major group are classified into the following minor groups: 121 Business Services and Administration Managers 122 Sales, Marketing and Development Managers Notes Specialized qualifications and extensive experience relevant to one or more occupations classified in Major Group 2: Professionals, or Major Group 3: Technicians and Associate Professionals, are usually required. Regional managers and other senior managers who coordinate and supervise the activities of subordinate managers who have a diverse range of functional responsibilities are included in Unit Group 1120: Managing Directors and Chief Executives.
has super-classes
Occupation c
has members
Administrative and commercial managers ni

Agricultural, forestry and fishery labourersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C92

Agricultural, forestry and fishery labourers perform simple and routine tasks in the production of crops and livestock, cultivation and maintenance of gardens and parks, exploitation and conservation of forests, and conduct of aquaculture and fisheries operations. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: digging, raking and shovelling using hand tools; loading, unloading and stacking supplies, produce and other materials; watering, thinning, weeding and tending crops by hand or using hand tools; planting, harvesting, picking and collecting produce by hand; feeding, watering and cleaning animals and keeping their quarters clean; monitoring livestock and reporting on their condition; preparing and operating nets, lines and other fishing tackle and deck equipment; grading, sorting, bunching and packing produce into containers; performing minor repairs on fixtures, buildings, equipment, vessels and fences. Occupations in this sub-major group are classified into the following minor group: 921 Agricultural, Forestry and Fishery Labourers
has super-classes
Occupation c
has members
Agricultural, forestry and fishery labourers ni

alemtuzumabc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L04AA34

has super-classes
Pharmacologic Substance c
has members
l04 a a34 ni

allergic disease test diagnostic agentsc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/V04CL

has super-classes
Pharmacologic Substance c
has members
v04 c l ni

alprazolamc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N05BA12

has super-classes
Pharmacologic Substance c
has members
n05 b a12 ni

ALSFRSc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ALSFRS

Amyotrophic Lateral Sclerosis Functional Rating Scale.
has super-classes
Questionnaire c
is in domain of
alsfrs-tot dp, alsfrs_1 dp, alsfrs_2 dp, alsfrs_3 dp, alsfrs_4 dp, alsfrs_5 dp, alsfrs_6 dp, alsfrs_7 dp, alsfrs_8 dp, alsfrs_9 dp, alsfrs_old10 dp, bulbar subscore dp, motor subscore dp

ALSFRS-Rc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ALSFRS-R

Revised Amyotrophic Lateral Sclerosis Functional Rating Scale.
has super-classes
Questionnaire c
is in domain of
Respiratory subscore. Sum of items 10, 11 and 12. dp, alsfrs-r-tot dp, alsfrs_1 dp, alsfrs_10 dp, alsfrs_11 dp, alsfrs_12 dp, alsfrs_2 dp, alsfrs_3 dp, alsfrs_4 dp, alsfrs_5 dp, alsfrs_6 dp, alsfrs_7 dp, alsfrs_8 dp, alsfrs_9 dp, bulbar subscore dp, motor subscore dp

amantadinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N04BB01

has super-classes
Pharmacologic Substance c
has members
n04 b b01 ni

amiodaronec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C01BD01

has super-classes
Pharmacologic Substance c
has members
c01 b d01 ni

amitriptylinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06AA09

has super-classes
Pharmacologic Substance c
has members
amitriptyline ni

amlodipinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C08CA01

has super-classes
Pharmacologic Substance c
has members
c08 c a01 ni

amyotrophic lateral sclerosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/MONDO_0004976

has super-classes
Disease or Disorder c
has members
Amyotrophic Lateral Sclerosis ni
is also defined as
named individual

anatomical structurec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0000061

Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome.
has sub-classes
Brain Stem c, Eye c, Limb c, Spinal Cord c, abdominal fascia c, bone spine c, brain c, cervical region of vertebral column c, cervical spinal cord c, head c, lumbosacral nerve plexus c, neck c, pelvic complex c, thoracic skeleton c, thoracic spinal cord c
is in range of
area op, site op, surgicalArea op, symptomArea op, traumaArea op
has members
anatomical structure ni, head-neck ni

Anemiac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2869

has super-classes
Disease or Disorder c
has members
Anemia ni
is also defined as
named individual

Ann Arbor Stage IV T-Cell Non-Hodgkin Lymphomac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C8668

has super-classes
Disease or Disorder c
has members
Ann Arbor Stage IV T-Cell Non-Hodgkin Lymphoma ni
is also defined as
named individual

Anxiety Disorderc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2878

has super-classes
Disease or Disorder c
has members
Anxiety ni
is also defined as
named individual

Armed forces occupations, other ranksc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C03

Armed forces occupations, other ranks include all conscripted and non-conscripted members of the armed forces except commissioned and non-commissioned officers. They perform specific military tasks and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. Most occupations in this sub-major group require skills at the first ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 031 Armed Forces Occupations, Other Ranks Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.
has super-classes
Occupation c
has members
Armed forces occupations, other ranks ni

Asian - ethnic groupc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/315280000

has super-classes
Ethnic group c
has members
Asian - ethnic group ni
is also defined as
named individual

Aspiration Pneumonitisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34932

has super-classes
Disease or Disorder c
has members
Aspiration Pneumonitis ni
is also defined as
named individual

Assemblersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C82

Assemblers assemble prefabricated parts or components to form subassemblies, products and equipment, according to procedures strictly laid down. The products worked on may be moved from one worker to the next along assembly lines. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: assembling components into various types of product and equipment, according to strictly laid down procedures; reviewing work orders, specifications, diagrams and drawings to determine materials needed and assembly instructions; recording production and operational data on specified forms; inspecting and testing completed components and assemblies, wiring installations and circuits; rejecting faulty assemblies and components. Occupations in this sub-major group are classified into the following minor group: 821 Assemblers
has super-classes
Occupation c
has members
Assemblers ni

atenololc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C07AB03

has super-classes
Pharmacologic Substance c
has members
c07 a b03 ni

atorvastatinc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C10AA05

has super-classes
Pharmacologic Substance c
has members
c10 a a05 ni

Atrial Fibrillationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50466

has super-classes
Disease or Disorder c
has members
Atrial Fibrillation ni
is also defined as
named individual

Atrial Flutterc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C51224

has super-classes
Disease or Disorder c
has members
Atrial Flutter ni
is also defined as
named individual

Auntc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71405

has super-classes
Relative c
has members
Aunt ni
is also defined as
named individual

Autoimmune Diseasec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2889

has super-classes
Disease or Disorder c
has members
Autoimmune Disease ni
is also defined as
named individual

azathioprinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L04AX01

has super-classes
Pharmacologic Substance c
has members
l04 a x01 ni

baclofenc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/M03BX01

has super-classes
Pharmacologic Substance c
has members
baclofen ni

Baker Cystc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34935

has super-classes
Disease or Disorder c
has members
Baker Cyst ni
is also defined as
named individual

barbexaclonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AA04

has super-classes
Pharmacologic Substance c
has members
n03 a a04 ni

Basal Cell Carcinomac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C156767

has super-classes
Disease or Disorder c
has members
Basal Cell Carcinoma ni
is also defined as
named individual

Before Onsetc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Before_Onset

The events occurring before onset.
has super-classes
Event c
is in domain of
howLong dp

betamethasonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/H02AB01

has super-classes
Pharmacologic Substance c
has members
h02 a b01 ni

bisoprololc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C07AB07

has super-classes
Pharmacologic Substance c
has members
c07 a b07 ni

Black Africanc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/18167009

has super-classes
Ethnic group c
has members
Black African ni
is also defined as
named individual

Blepharitisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C112183

has super-classes
Disease or Disorder c
has members
Blepharitis ni
is also defined as
named individual

Blepharospasmc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C118723

has super-classes
Disease or Disorder c
has members
Blepharospasm ni
is also defined as
named individual

bone spinec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0013706

Semantic Types: Body Location or Region
is equivalent to
c2337179 c
has super-classes
anatomical structure c
has members
bone spine ni

botulinum toxinc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/M03AX01

has super-classes
Pharmacologic Substance c
has members
m03 a x01 ni

Bowel and Bladderc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Bowel_and_Bladder

has super-classes
Symptom c
has members
Bowel and Bladder ni

Bowel Obstructionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C9175

has super-classes
Disease or Disorder c
has members
Bowel Obstruction ni
is also defined as
named individual

brainc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0000955

has super-classes
anatomical structure c
has members
brain ni
is also defined as
named individual

Brain Stemc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12441

has super-classes
anatomical structure c
has members
Brain Stem ni
is also defined as
named individual

Brainstem Symptomc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Brainstem_Symptom

has super-classes
Symptom c
has members
Brainstem Symptom ni

bromazepamc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N05BA08

has super-classes
Pharmacologic Substance c
has members
n05 b a08 ni

Brotherc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25289

has super-classes
Sibling c
has members
Brother ni
is also defined as
named individual

Brown-Sequard Syndromec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C84601

has super-classes
Disease or Disorder c
has members
Brown-Sequard Syndrome ni
is also defined as
named individual

Building and related trades workers, excluding electriciansc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C71

Building and related trades workers construct, maintain and repair buildings; erect and repair foundations, walls and structures of brick, stone and similar materials; shape and finish stone for building and other purposes. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, the materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: constructing, maintaining and repairing buildings and other structures, using traditional and/or modern building techniques; constructing and repairing foundations, walls and structures of brick, stone and similar materials; breaking quarried stone into slabs or blocks; cutting, shaping and finishing stone for building, ornamental, monumental and other purposes; erecting reinforced concrete frameworks and structures as well as finishing and repairing cement surfaces; cutting, shaping, assembling and maintaining wooden structures and fittings; performing miscellaneous construction and building maintenance tasks. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 711 Building Frame and Related Trades Workers 712 Building Finishers and Related Trades Workers 713 Painters, Building Structure Cleaners and Related Trades Workers
has super-classes
Occupation c
has members
Building and related trades workers, excluding electricians ni

Business and administration associate professionalsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C33

Business and administration associate professionals perform mostly technical tasks connected with the practical application of knowledge relating to financial accounting and transaction matters, mathematical calculations, human resource development, selling and buying financial instruments, specialized secretarial tasks, and enforcing or applying government rules. Also included are workers who provide business services such as customs clearance, conference planning, job placements, buying and selling real estate or bulk commodities, and serving as agents for performers such as athletes and artists. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include recording and transmitting buy and sell orders for securities, stocks, bonds or other financial instruments and for foreign exchange for future or immediate delivery; submitting credit and loan applications to management with recommendations for approval or rejection; approving or rejecting applications within authorized limits ensuring that credit standards of the institution are respected; maintaining complete records of all financial transactions of an undertaking according to general bookkeeping principles, with guidance from accountants; assisting in planning and performing mathematical, statistical, actuarial, accounting and related calculations; selling and buying financial instruments. Occupations in this sub-major group are classified into the following minor groups: 331 Financial and Mathematical Associate Professionals 332 Sales and Purchasing Agents and Brokers 333 Business Services Agents 334 Administrative and Specialized Secretaries 335 Government Regulatory Associate Professionals
has super-classes
Occupation c
has members
Business and administration associate professionals ni

Business and administration professionalsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C24

Business and administration professionals perform analytical, conceptual and practical tasks to provide services in financial matters, human resource development, public relations, marketing and sales in the technical, medical, information and communications technology areas; and conduct reviews of organizational structures, methods and systems as well as quantitative analyses of information affecting investment programmes. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: collecting, analysing and interpreting information on the financial viability, cost structures and trading effectiveness of organizations; conducting audits, preparing financial statements and controlling treasury systems for organizations; developing and reviewing financial plans and strategies, executing buy and sell orders, and negotiating the purchase and sale of commodities; developing, implementing and evaluating staff recruitment, training and development programmes; researching, developing and implementing marketing and public relations campaigns; studying and developing methods and policies to improve and promote government and business operations and effectiveness; acquiring and updating knowledge of employers’ and competitors’ goods and services, and of market conditions; assessing customers’ needs and explaining and demonstrating goods and services to them. Occupations in this sub-major group are classified into the following minor group: 241 Finance Professionals 242 Administration Professionals 243 Sales, Marketing and Public Relations Professionals
has super-classes
Occupation c
has members
Business and administration professionals ni

C9orf72c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OGG_3000203228

This gene may play a role in cell death. [Definition Source: NCI]
has super-classes
gene c
has members
C9orf72 ni

candesartan and diureticsc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C09DA06

has super-classes
Pharmacologic Substance c
has members
c09 d a06 ni

cannabinoidsc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N02BG10

has super-classes
Pharmacologic Substance c
has members
n02 b g10 ni

carbamazepinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AF01

has super-classes
Pharmacologic Substance c
has members
n03 a f01 ni

Cardiovascular Disorderc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2931

has super-classes
Disease or Disorder c
has members
Cardiovascular Disorder ni
is also defined as
named individual

Cardioversionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C70911

has super-classes
Disease or Disorder c
has members
Cardioversion ni
is also defined as
named individual

Caucasianc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/14045001

has super-classes
Ethnic group c
has members
Caucasian ni
is also defined as
named individual

Cerebellar Symptomc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Cerebellar_Symptom

has super-classes
Symptom c
has members
Cerebellar Symptom ni

cervical region of vertebral columnc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0006072

That portion of the spine comprising the cervical vertebrae. The neck area of the spine. [ http://medical-dictionary.thefreedictionary.com/ ]
has super-classes
anatomical structure c
has members
cervical region of vertebral column ni

cervical spinal cordc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0002726

has super-classes
anatomical structure c
has members
cervical spinal cord ni
is also defined as
named individual

Chief executives, senior officials and legislatorsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C11

Chief executives, senior officials and legislators formulate and review the policies, and plan, direct, coordinate and evaluate the overall activities of enterprises, governments and other organizations with the support of other managers. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level . Tasks performed by workers in this sub-major group usually include: presiding over or participating in the proceedings of legislative bodies, boards of directors and committees; formulating and advising on the policy budgets, laws and regulations of enterprises, governments and other organizations; establishing objectives for enterprises, government departments or agencies and other organizations; formulating or approving and evaluating programmes and policies and procedures for their implementation; ensuring appropriate systems and procedures are developed and implemented to provide budgetary control; authorizing material, human and financial resources to implement policies and programmes; monitoring and evaluating performance of the organization or enterprise; selecting or approving the selection of senior staff; performing ceremonial duties and representing the enterprise, government, organization or community at official occasions and in meetings, negotiations, conventions and public hearings. Occupations in this sub-major group are classified into the following minor groups: 111 Legislators and Senior Officials 112 Managing Directors and Chief Executives
has super-classes
Occupation c
has members
Chief executives, senior officials and legislators ni

cinnarizinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N07CA02

has super-classes
Pharmacologic Substance c
has members
n07 c a02 ni

cinnarizine, combinationsc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N07CA52

has super-classes
Pharmacologic Substance c
has members
n07 c a52 ni

citalopramc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06AB04

has super-classes
Pharmacologic Substance c
has members
n06 a b04 ni

Citiesc back to ToC or Class ToC

IRI: https://uts.nlm.nih.gov/uts/umls/concept/C0008848

A large or important municipality of a country, usually a major metropolitan center. (MSH)
has super-classes
Place c
has members
Cities ni

cladribinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L01BB04

has super-classes
Pharmacologic Substance c
has members
l01 b b04 ni

Cleaners and helpersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C91

Cleaners and helpers perform various tasks in private households, hotels, offices, hospitals and other establishments, as well as in aircraft, trains, coaches, trams and similar vehicles, in order to keep the interiors and fixtures clean, and launder and press garments and textiles by hand. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: sweeping or vacuum cleaning; washing and polishing floors, furniture and other objects; taking care of linen and bedmaking; helping with preparation of meals and cleaning in kitchens; washing and cleaning cars and windows; pressing or laundering garments and textiles by hand. Occupations in this sub-major group are classified into the following minor groups: 911 Domestic, Hotel and Office Cleaners and Helpers 912 Vehicle, Window, Laundry and Other Hand Cleaning Workers
has super-classes
Occupation c
has members
Cleaners and helpers ni

clinical assessmentc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/MAXO_0000487

A measurement performed in a clinical setting using clinician's observations and instrument data to inform patient care and research. [database_cross_reference: PMID:2647562][database cross reference: PMID:2647562][database_cross_reference: PMID:2647562][database cross reference: PMID:2647562][database_cross_reference: PMID:2647562][database cross reference: PMID:2647562]
has super-classes
Diagnostic Procedure c
is in domain of
Height dp, MS type dp, Muscle strength assessed by manual testing dp, Neurophysiological changes dp, NoEvidenceofDiseaseActivity Status dp, Weight dp, bmi dp, cognitive changes dp, cognitive symptoms dp, mixedMN dp, moreThan10PercentWeightloss dp, predominant impairment dp, predominant side dp, prevalentLMN dp, prevalentUMN dp, rate of disease progression dp

Clinical Trialc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71104

is equivalent to
c0008976 c
is in domain of
isAboutDisease op, pertain op
is in range of
partecipate op
has members
ClinicalTrial ALS Lisbon 1 ni, ClinicalTrial ALS Madrid 1 ni, ClinicalTrial ALS Turin 1 ni, ClinicalTrial MS Pavia 1 ni
is also defined as
named individual

Clinical Trial Participationc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Clinical_Trial_Participation

The participation in a clinical trial.
is in domain of
clinicalTrialDescription dp, endDate dp, endReason dp, partecipate op, startDate dp
is in range of
enrolledIn op

clonazepamc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AE01

has super-classes
Pharmacologic Substance c
has members
n03 a e01 ni

clopidogrelc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/B01AC04

has super-classes
Pharmacologic Substance c
has members
b01 a c04 ni

Commissioned armed forces officersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C01

Commissioned armed forces officers provide leadership and management to organizational units in the armed forces and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. This group includes all members of the armed forces holding the rank of second lieutenant (or equivalent) or higher. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 011 Commissioned Armed Forces Officers Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.
has super-classes
Occupation c
has members
Commissioned armed forces officers ni

Congenital Adrenal Hyperplasiac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34360

has super-classes
Disease or Disorder c
has members
Congenital Adrenal Hyperplasia ni
is also defined as
named individual

cortisone treatmentc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/cortisone_treatment

This entity refers to a cortisone treatment associated to a relapse.
has super-classes
Pharmacologic Substance c
has members
cortisone treatment ni

Critical Episodec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Critical_Episode

has super-classes
Symptom c
has members
Critical Episode ni

CSF Analysisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C173272

has super-classes
Surgical Procedure c
is in domain of
IgG dp, IgG-index dp, Q-albumin dp, albumin dp, bloodSugar dp, cerebrospinalFluid dp, leukocyteCounts dp, numberOfOligoclonalBands dp, oligoclonalBands dp, protein dp, typeOfOligoclonalBands dp
is also defined as
named individual

Customer services clerksc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C42

Customer services clerks deal with clients in connection with money-handling operations, travel arrangements, requests for information, making appointments, operating telephone switchboards, and interviewing for surveys or to complete applications for eligibility for services. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: performing money-handling operations in banks, post offices, betting and gambling establishments, or dealing with travel arrangements; supplying information requested by clients and making appointments; operating telephone switchboards; greeting and receiving visitors; interviewing survey respondents; interviewing applicants for services. Occupations in this sub-major group are classified into the following minor groups: 421 Tellers, Money Collectors and Related Clerks 422 Client Information Workers
has super-classes
Occupation c
has members
Customer services clerks ni

cyclophosphamidec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L01AA01

has super-classes
Pharmacologic Substance c
has members
l01 a a01 ni

Daughterc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25165

has super-classes
First Degree Relative c
has members
Daughter ni
is also defined as
named individual

Deep Vein Thrombosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C49343

has super-classes
Disease or Disorder c
has members
Deep Vein Thrombosis ni
is also defined as
named individual

deflazacortc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/H02AB13

has super-classes
Pharmacologic Substance c
has members
h02 a b13 ni

denosumabc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/M05BX04

has super-classes
Pharmacologic Substance c
has members
m05 b x04 ni

Depressionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2982

has super-classes
Disease or Disorder c
has members
Depression ni
is also defined as
named individual

dexamethasonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/H02AB02

has super-classes
Pharmacologic Substance c
has members
h02 a b02 ni

Diabetes Mellitusc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2985

has super-classes
Disease or Disorder c
has sub-classes
Type 1 Diabetes Mellitus c, Type 2 Diabetes Mellitus c
has members
Diabetes Mellitus ni
is also defined as
named individual

Diagnosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15220

has super-classes
Event c
is in domain of
criteria dp
is also defined as
named individual

Diagnostic Imagingc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C16502

has super-classes
Diagnostic Procedure c
has sub-classes
Magnetic Resonance Imaging c, Positron Emission Tomography c, Tomography, Optical Coherence c
is in domain of
area op
is also defined as
named individual

Diagnostic Procedurec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C18020

has super-classes
Intervention or Procedure c
has sub-classes
Diagnostic Imaging c, Evoked Potentials c, Expanded Disability Status Scale c, Hematology Test c, Pulmonary Function Test c, Questionnaire c, clinical assessment c
is also defined as
named individual

diazepamc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N05BA01

has super-classes
Pharmacologic Substance c
has members
n05 b a01 ni

dimethyl fumaratec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L04AX07

has super-classes
Pharmacologic Substance c
has members
l04 a x07 ni

Disease Modifying Therapyc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Disease_Modifying_Therapy

has super-classes
Therapeutic Procedure c
is in domain of
seriousAdversarialEvent dp

Dizzinessc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C37943

has super-classes
Symptom c
has members
Dizziness ni
is also defined as
named individual

Drivers and mobile plant operatorsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C83

Drivers and mobile plant operators drive and tend trains and motor vehicles, or drive, operate and monitor industrial and agricultural machinery and equipment, or execute deck duties on board ship and other water-borne craft. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: driving and tending trains and motor vehicles; driving, operating and monitoring mobile industrial and agricultural machinery and equipment; carrying out deck duties on board ship and other water-borne craft. Occupations in this sub-major group are classified into the following minor groups: 831 Locomotive Engine Drivers and Related Workers 832 Car, Van and Motorcycle Drivers 833 Heavy Truck and Bus Drivers 834 Mobile Plant Operators 835 Ships’ Deck Crews and Related Workers
has super-classes
Occupation c
has members
Drivers and mobile plant operators ni

duloxetinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06AX21

has super-classes
Pharmacologic Substance c
has members
n06 a x21 ni

Dyslipidemiac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C80385

has super-classes
Disease or Disorder c
has members
Dyslipidemia ni
is also defined as
named individual

Electrical and electronic trades workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C74

Electrical and electronics trades workers install, fit and maintain electrical wiring systems and machinery and other electrical apparatus, electrical transmission and supply lines and cables, and electronic and telecommunications equipment and systems. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: installing, maintaining, fitting and adjusting electrical and electronic wiring systems, machinery and equipment; examining blueprints, wiring diagrams and specifications to determine sequences and methods of operation; inspecting and testing electrical and electronic systems, equipment, cables and machinery to identify hazards, defects and the need for adjustment or repair; installing, maintaining and repairing electrical and telecommunications transmission lines; joining electrical, telecommunications and data cables; maintaining, troubleshooting, fitting, adjusting, testing and repairing electronic equipment such as commercial and office machines, electronic instruments and control systems, computers, and telecommunications and data transmission equipment. Occupations in this sub-major group are classified into the following minor groups: 741 Electrical Equipment Installers and Repairers 742 Electronics and Telecommunications Installers and Repairers
has super-classes
Occupation c
has members
Electrical and electronic trades workers ni

Elementary occupationsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C9

Elementary occupations involve the performance of simple and routine tasks which may require the use of hand-held tools and considerable physical effort. Most occupations in this major group require skills at the first ISCO skill level. Tasks performed by workers in elementary occupations usually include: cleaning, restocking supplies and performing basic maintenance in apartments, houses, kitchens, hotels, offices and other buildings; washing cars and windows; helping in kitchens and performing simple tasks in food preparation; delivering messages or goods; carrying luggage and handling baggage and freight; stocking vending-machines or reading and emptying meters; collecting and sorting refuse; sweeping streets and similar places; performing various simple farming, fishing, hunting or trapping tasks; performing simple tasks connected with mining, construction and manufacturing including product-sorting; packing and unpacking produce by hand, and filling shelves; providing various street services; pedalling or hand-guiding vehicles to transport passengers and goods; driving animal-drawn vehicles or machinery. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 91 Cleaners and Helpers 92 Agricultural, Forestry and Fishery Labourers 93 Labourers in Mining, Construction, Manufacturing and Transport 94 Food Preparation Assistants 95 Street and Related Sales and Services Workers 96 Refuse Workers and Other Elementary Workers
has super-classes
Occupation c
has members
Elementary occupations ni

enalaprilc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C09AA02

has super-classes
Pharmacologic Substance c
has members
c09 a a02 ni

Endometriosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3014

has super-classes
Disease or Disorder c
has members
Endometriosis ni

Epidermal Inclusion Cystc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3134

has super-classes
Disease or Disorder c
has members
Epidermal Inclusion Cyst ni
is also defined as
named individual

Essential Hypertensionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3478

Hypertension that presents without an identifiable cause. [Definition Source: NCI]
has super-classes
Disease or Disorder c
has members
Essential Hypertension ni

Evoked Potentialsc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OMIT_0006295

Evoked potentials (EPs) are the electrical signals produced by the nervous system in response to an external stimulus.
has super-classes
Diagnostic Procedure c
has sub-classes
Evoked Potentials, Auditory c, Evoked Potentials, Motor c, Evoked Potentials, Somatosensory c, Evoked Potentials, Visual c
is in domain of
location dp, potentialValue dp

Evoked Potentials, Auditoryc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OMIT_0006296

Auditory evoked potentials (AEPs), also referred to as evoked responses, are a record of the time it takes nerves in the auditory system to respond to sound and electrical stimulation.
has super-classes
Evoked Potentials c

Evoked Potentials, Motorc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OMIT_0019166

Motor evoked potentials (MEPs) are the electrical signals recorded from the descending motor pathways or from muscles following stimulation of motor pathways within the brain.
has super-classes
Evoked Potentials c

Evoked Potentials, Somatosensoryc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OMIT_0006297

Somatosensory evoked potentials (SSEPs) are brain and spinal cord responses elicited by sensory stimuli.
has super-classes
Evoked Potentials c

Evoked Potentials, Visualc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OMIT_0006298

A visual evoked potential is an evoked potential caused by a visual stimulus, such as an alternating checkerboard pattern on a computer screen.
has super-classes
Evoked Potentials c

Expanded Disability Status Scalec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C98302

has super-classes
Diagnostic Procedure c
is in domain of
ambulation dp, bowel and bladder dp, brainstem dp, cerebellar dp, cerebral functions dp, other dp, pyramidal dp, sensory dp, totalEDSS dp, visual function dp
is also defined as
named individual

Eyec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12401

has super-classes
anatomical structure c
is also defined as
named individual

Eye Symptomc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Eye_Symptom

has super-classes
Symptom c
has members
Eye Symptom ni

Facial Nerve Palsyc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26769

has super-classes
Disease or Disorder c
has members
Facial Nerve Palsy ni
is also defined as
named individual

fampridinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N07XX07

has super-classes
Pharmacologic Substance c
has members
n07 x x07 ni

Fatherc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25174

has super-classes
First Degree Relative c
has members
Father ni
is also defined as
named individual

Fatiguec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3036

has super-classes
Symptom c
has members
Fatigue ni
is also defined as
named individual

Feverc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3038

has super-classes
Disease or Disorder c, Symptom c
has members
Fever ni
is also defined as
named individual

fingolimodc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L04AA27

has super-classes
Pharmacologic Substance c
has members
l04 a a27 ni

First Degree Relativec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C21481

has super-classes
Relative c
has sub-classes
Daughter c, Father c, Mother c, Son c
has members
First Degree Relative ni
is also defined as
named individual

Flu-Like Symptomsc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C78302

has super-classes
Disease or Disorder c
has members
Flu-Like Symptoms ni
is also defined as
named individual

fluoxetinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06AB03

has super-classes
Pharmacologic Substance c
has members
n06 a b03 ni

Food preparation assistantsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C94

Food preparation assistants prepare and cook to order a small variety of pre-cooked food or beverages, clear tables, clean kitchen areas and wash dishes. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing simple or pre-prepared foods and beverages such as sandwiches, pizzas, fish and chips, salads and coffee; washing, cutting, measuring and mixing foods for cooking; operating cooking equipment such as grills, microwaves and deep-fat fryers; cleaning kitchens, food preparation areas and service areas; cleaning cooking and general utensils used in kitchens and restaurants. Occupations in this sub-major group are classified into the following minor group: 941 Food Preparation Assistants
has super-classes
Occupation c
has members
Food preparation assistants ni

Food processing, wood working, garment and other craft and related trades workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C75

Food processing, woodworking, garment and other craft and related trades workers treat and process agricultural and fisheries raw materials into food and other products, and produce and repair goods made of wood, textiles, fur, leather or other materials. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: treating and processing meat, fish, grain, fruit, vegetables and related materials into food stuffs, and tobacco into tobacco products; tasting and grading food products and beverages; treating and processing natural fibres, skins and hides; making and repairing furniture and other goods made of wood; preparing hides, skins and pelts for further use; making and repairing textiles, garments, hats, shoes and related products. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 751 Food Processing and Related Trades Workers 752 Wood Treaters, Cabinet-makers and Related Trades Workers 753 Garment and Related Trades Workers 754 Other Craft and Related Workers
has super-classes
Occupation c
has members
Food processing, wood working, garment and other craft and related trades workers ni

furosemidec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C03CA01

has super-classes
Pharmacologic Substance c
has members
c03 c a01 ni

FUSc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OGG_3000002521

This gene is involved in gene expression, genomic integrity and RNA processing. [Definition Source: NCI]
has super-classes
gene c
has members
FUS ni

gabapentinc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AX12

has super-classes
Pharmacologic Substance c
has members
n03 a x12 ni

genec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OGG_0000000002

A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule.
has sub-classes
C9orf72 c, FUS c, SOD1 c, TARDBP c
is in domain of
kind dp, open box dp
is in range of
hasGene op

General and keyboard clerksc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C41

General and keyboard clerks record, organize, store and retrieve information and perform a wide range of clerical and administrative tasks according to established procedures. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: recording, preparing, sorting, classifying and filing information; sorting, opening and sending mail; preparing reports and correspondence of a routine nature; photocopying and faxing documents; operating personal computers, word processors or typewriters to record, input and process text and data; proofreading and correcting copy; preparing invoices and checking figures. Occupations in this sub-major group are classified into the following minor groups: 411 General Office Clerks 412 Secretaries (general) 413 Keyboard Operators
has super-classes
Occupation c
has members
General and keyboard clerks ni

glatiramer acetatec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L03AX13

has super-classes
Pharmacologic Substance c
has members
glatiramer acetate ni

Glaucomac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26782

Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor. [Definition Source: NCI]
has super-classes
Disease or Disorder c
has members
Glaucoma ni

Grand Relativec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71388

has super-classes
Relative c
has sub-classes
Grandchild c, Grandparent c
has members
Grand Relative ni
is also defined as
named individual

Grandchildc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71397

has super-classes
Grand Relative c, Second Degree Relative c
has members
Grandchild ni
is also defined as
named individual

Grandparentc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71385

has super-classes
Grand Relative c
has members
Grandparent ni
is also defined as
named individual

Handicraft and printing workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C73

Handicraft and printing workers combine artistic and manual skills to design, produce, maintain and decorate precision instruments, musical instruments, jewellery and other precious metals, pottery, porcelain and glassware, items made of wood or textile, leather or related materials, and printed products such as books, newspapers and magazines. They apply traditional and/or recently developed techniques to carve, mould, assemble, weave and decorate various articles; to compose and set type prior to printing; to set up and operate printing presses; to bind and finish printed products; and to prepare stencils and operate screen printing equipment. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work may be carried out by hand or involve the use of hand tools and hand-held power tools, and in some cases the set-up and operation of machinery and machine tools. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: making and repairing nautical, meteorological, optical and other precision instruments and equipment; making and repairing musical instruments; making jewellery and precious metalware; making pottery, porcelain ware, ceramics and glassware; painting and decorating various articles; producing handicraft articles in wood or textile, leather and related materials; performing printing or book-binding tasks. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 731 Handicraft Workers 732 Printing Trades Workers
has super-classes
Occupation c
has members
Handicraft and printing workers ni

Hashimoto Thyroiditisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C27191

has super-classes
Disease or Disorder c
has members
Hashimoto Thyroiditis ni
is also defined as
named individual

headc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0000033

The head is the anterior-most division of the body [GO]. [ http://en.wikipedia.org/wiki/Head http://amigo.geneontology.org/amigo/term/GO:0060322 ]
has super-classes
anatomical structure c
has members
head ni

Health associate professionalsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C32

Health associate professionals perform technical and practical tasks to support diagnosis and treatment of illness, disease, injuries and impairments in humans and animals, and to support implementation of health care, treatment and referral plans usually established by medical, veterinary, nursing and other health professionals. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in the sub-major group usually include: testing and operating medical imaging equipment and administering radiation therapy; performing clinical tests on specimens of bodily fluids and tissues; preparing medications and other pharmaceutical compounds under the guidance of pharmacists; designing, fitting, servicing and repairing medical and dental devices and appliances; providing nursing and personal care and midwifery support services; using herbal and other therapies based on theories, beliefs and experiences originating in specific cultures. Occupations in this sub-major group are classified into the following minor groups: 321 Medical and Pharmaceutical Technicians 322 Nursing and Midwifery Associate Professionals 323 Traditional and Complementary Medicine Associate Professionals 324 Veterinary Technicians and Assistants 325 Other Health Associate Professionals
has super-classes
Occupation c
has members
Health associate professionals ni

Health professionalsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C22

Health professionals conduct research,; improve or develop concepts, theories and operational methods; and apply scientific knowledge relating to medicine, nursing, dentistry, veterinary medicine, pharmacy, and promotion of health. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research and obtaining scientific knowledge through the study of human and animal disorders and illnesses and ways of treating them; advising on or applying preventive and curative measures, or promoting health; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 221 Medical Doctors 222 Nursing and Midwifery Professionals 223 Traditional and Complementary Medicine Professionals 224 Paramedical Practitioners 225 Veterinarians 226 Other Health Professionals Note In using ISCO in applications that seek to identify, describe or measure the health workforce, it should be noted that a number of professions considered to be a part of the health workforce are classified in groups other than Sub-major Group 22: Health Professionals. Such occupations include but are not restricted to: addictions counsellors, biomedical engineers, clinical psychologists and medical physicists.
has super-classes
Occupation c
has members
Health professionals ni

Heart Disorderc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3079

has super-classes
Disease or Disorder c
has members
Heart Disorder ni
is also defined as
named individual

Heart Failurec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50577

has super-classes
Disease or Disorder c
has members
Heart Failure ni
is also defined as
named individual

Hematology Testc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C49286

has super-classes
Diagnostic Procedure c
is in domain of
Albumin level dp, Albumin lower range dp, Albumin upper range dp, CK level dp, CK lower range dp, CK upper range dp, Creatinine level dp, Creatinine lower range dp, Creatinine upper range dp, HBV_test dp, HCV_test dp, HDL Cholesterol level dp, HDL Cholesterol lower range dp, HDL Cholesterol upper range dp, HIV_test dp, LDL Cholesterol level dp, LDL Cholesterol lower range dp, LDL Cholesterol upper range dp, MNDN-PV unologic dp, Neutralizing anti-IFN antibody dp, Thyroid Function dp, Total Cholesterol level dp, Total Cholesterol lower range dp, Total Cholesterol upper range dp, Triglycerides level dp, Triglycerides lower range dp, Triglycerides upper range dp, Vitamin D Level dp, anti-Tg dp, anti-TgNormal dp, anti-chickenpox antibody dp, bloodAMA dp, bloodAMANormal dp, bloodANA dp, bloodANANormal dp, bloodANCA dp, bloodANCANormal dp, bloodAPCA dp, bloodAPCANormal dp, bloodASMA dp, bloodASMANormal dp, bloodAbTMS dp, bloodAbTMSNormal dp, bloodAlbuminNormal dp, bloodAlkalinePhosphatase dp, bloodAlkalinePhosphataseNormal dp, bloodAmylaseNormal dp, bloodAnti-DNA dp, bloodAnti-DNANormal dp, bloodAnti-LKM dp, bloodAnti-LKMNormal dp, bloodAnti-SSA_Ro dp, bloodAnti-SSA_RoNormal dp, bloodAnti-cardiolipin dp, bloodAnti-cardiolipinNormal dp, bloodAnti-transglutaminase dp, bloodAnti-transglutaminaseNormal dp, bloodBasophil dp, bloodBasophilNormal dp, bloodBilirubin dp, bloodBilirubinNormal dp, bloodCalcium dp, bloodCalciumNormal dp, bloodCreatinine dp, bloodCreatinineNormal dp, bloodEosinophil dp, bloodEosinophilNormal dp, bloodErythrocytes dp, bloodErythrocytesNormal dp, bloodFT3 dp, bloodFT3Normal dp, bloodFT4 dp, bloodFT4Normal dp, bloodGGT dp, bloodGGTNormal dp, bloodHemoglobin dp, bloodHemoglobinNormal dp, bloodJo1 dp, bloodJo1Normal dp, bloodLAC dp, bloodLACNormal dp, bloodLa dp, bloodLaNormal dp, bloodLeukocytes dp, bloodLeukocytesNormal dp, bloodLipaseNormal dp, bloodLymphocytes dp, bloodLymphocytesNormal dp, bloodMonocytes dp, bloodMonocytesNormal dp, bloodNeutrophil dp, bloodNeutrophilNormal dp, bloodPlatelet dp, bloodPlateletNormal dp, bloodRNP dp, bloodRNPNormal dp, bloodSGOT_AST dp, bloodSGOT_AST_Normal dp, bloodSGPT_ALT dp, bloodSGPT_ALT_Normal dp, bloodScl-70 dp, bloodScl-70Normal dp, bloodSm dp, bloodSmNormal dp, bloodTSH dp, bloodTSHNormal dp, bloodTotalProtein dp, bloodTotalProteinNormal dp, bloodUrea dp, bloodUreaNormal dp, bloodUricaemia dp, bloodUricaemiaNormal dp, hematologic dp, mantoux test dp, plasma beta-hCG dp, quantiferon TB Gold test dp, virological dp
is also defined as
named individual

Hepatitis A Infectionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3096

has super-classes
Disease or Disorder c
has members
Hepatitis A Infection ni
is also defined as
named individual

Herniac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34685

has super-classes
Disease or Disorder c
has sub-classes
Herniated Disk c, Lumbar Hernia c, Vertebral Hernia c
has members
Hernia ni
is also defined as
named individual

Herniated Diskc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Herniated_Disk

has super-classes
Hernia c
has members
Herniated Disk ni

Herpes Labialisc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Herpes_Labialis

has super-classes
Disease or Disorder c
has members
Herpes Labialis ni
is also defined as
named individual

Herpes Zosterc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71079

has super-classes
Disease or Disorder c
has members
Herpes Zoster ni
is also defined as
named individual

Herpetic Keratitisc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Herpetic_Keratitis

has super-classes
Disease or Disorder c
has members
Herpetic Keratitis ni
is also defined as
named individual

Hispanicc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/414408004

has super-classes
Ethnic group c
has members
Hispanic ni
is also defined as
named individual

Hospitality, retail and other services managersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C14

Hospitality, retail and other services managers plan, organize and direct the operations of establishments which provide accommodation, hospitality, retail and other services. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: planning and organizing special functions, sporting, gaming and entertainment activities and the range and mix of products, stock levels and service standards; promoting and selling goods and services; observing liquor, gaming, health and other laws and regulations; developing and reviewing policies, programmes and procedures concerning customer relations and goods and services provided; promoting facilities for conferences, conventions and trade shows to potential customers; organizing the purchase and maintenance of transport vehicles, equipment and fuel, and transporting goods; controlling the selection, training and supervision of staff; ensuring compliance with occupational health and safety regulations. Occupations in this sub-major group are classified into the following minor groups: 141 Hotel and Restaurant Managers 142 Retail and Wholesale Trade Managers 143 Other Services Managers Notes Sub-major Group 14: Hospitality, Retail and Other Services Managers is for managers of establishments that provide services directly to the public, usually in organizations that are too small to have hierarchies of managers. Managers responsible for planning, directing and coordinating the provision of specialized professional and technical services that usually require specialized qualifications are classified in various unit groups in Sub-major Groups 12: Administrative and Commercial Managers and 13: Production and Specialized Services Managers. Operators of small shops, guest houses, cafés, restaurants and bars for whom the management and supervision of staff is not a significant component of the work are classified in the relevant unit group in Sub-major Groups 51: Personal Services Workers or 52: Sales Workers, depending on the main tasks performed.
has super-classes
Occupation c
has members
Hospitality, retail and other services managers ni

hydrocortisonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/D07AA02

has super-classes
Pharmacologic Substance c
has members
d07 a a02 ni

hydrocortisonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/H02AB09

has super-classes
Pharmacologic Substance c
has members
h02 a b09 ni

hydroxychloroquinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/P01BA02

has super-classes
Pharmacologic Substance c
has members
p01 b a02 ni

Hypertensionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3117

has super-classes
Disease or Disorder c
has members
Hypertension ni
is also defined as
named individual

Hyperthyroidismc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3123

has super-classes
Disease or Disorder c
has members
Hyperthyroidism ni
is also defined as
named individual

Hypothyroidismc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26800

has super-classes
Disease or Disorder c
has sub-classes
Postoperative Hypothyroidism c
has members
Hypothyroidism ni
is also defined as
named individual

Increased involuntary muscle tone caused by central nervous system disorders that affect the regions interfering with voluntary movement. It results in gait, movement, and speech disturbances. Representative examples of disorders causing spasticity include brain or spinal cord injury, and multiple sclerosis. [Definition Source: NCI]c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C79750

has super-classes
Symptom c
has members
Spasticity ni
is also defined as
named individual

Infectious Mononucleosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34726

has super-classes
Disease or Disorder c
has members
Infectious Mononucleosis ni
is also defined as
named individual

Inflammationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_3137

has super-classes
Symptom c
is in domain of
associatedSubstance op
has members
Inflammation ni
is also defined as
named individual

Information and communications techniciansc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C35

Information and communications technicians provide support for the day-to-day running of computer systems, communications systems and networks, and perform technical tasks related to telecommunications, broadcast image and sound as well as other types of telecommunications signals on land, sea or in aircraft. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: providing assistance to information and communications systems users; installing new programs and equipment; establishing, operating and maintaining network and other data communications systems; installing, monitoring and supporting Internet and Intranet websites or web server hardware or software; modifying web pages; and performing web server backup and recovery operations; controlling equipment to record sound, edit and mix image and sound recordings; controlling and maintaining transmitting and broadcast systems and satellite systems for radio and television programmes; controlling and maintaining radio communications systems, satellite services and multiplex systems on land, sea or in aircraft; providing technical assistance connected with research and development of computer systems and telecommunications equipment, or testing prototypes; designing and preparing blueprints of circuitry according to the specifications given; providing technical supervision of the manufacture, utilization, maintenance and repair of telecommunications systems. Occupations in this sub-major group are classified into the following minor groups: 351 Information and Communications Technology Operations and User Support Technicians 352 Telecommunications and Broadcasting Technicians
has super-classes
Occupation c
has members
Information and communications technicians ni

Information and communications technology professionalsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C25

Information and communications technology professionals conduct research; plan, design, write, test, provide advice and improve information technology systems, hardware, software and related concepts for specific applications; develop associated documentation including principles, policies and procedures; and design, develop, control, maintain and support databases and other information systems to ensure optimal performance and data integrity and security. Tasks performed by workers in this sub-major group usually include: researching information technology use in business functions; identifying areas for improvement and researching the theoretical aspects and operational methods for the use of computers; evaluating, planning and designing hardware or software configurations for specific applications including for Internet, Intranet and multimedia systems; designing, writing, testing and maintaining computer programs; designing and developing database architecture and database management systems; developing and implementing security plans and data administration policy, and administering computer networks and related computing environments; analysing, developing, interpreting and evaluating complex system design and architecture specifications, data models and diagrams in the development, configuration and integration of computer systems. Occupations in this sub-major group are classified into the following minor groups: 251 Software and Applications Developers and Analysts 252 Database and Network Professionals
has super-classes
Occupation c
has members
Information and communications technology professionals ni

Institutionc back to ToC or Class ToC

IRI: https://dbpedia.org/ontology/institution

has members
Brainteaser Consortium ni

interferon beta-1ac back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L03AB07

has super-classes
Pharmacologic Substance c
has members
interferon beta-1a ni

interferon beta-1bc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L03AB08

has super-classes
Pharmacologic Substance c
has members
l03 a b08 ni

Interstitial Pneumoniac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C27006

has super-classes
Disease or Disorder c
has members
Interstitial Pneumonia ni
is also defined as
named individual

Iridocyclitisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34736

has super-classes
Disease or Disorder c
has members
Iridocyclitis ni
is also defined as
named individual

Iron-Deficiency Anemiac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C84484

has super-classes
Disease or Disorder c
has members
Iron-Deficiency Anemia ni
is also defined as
named individual

Kingsc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Kings

King’s staging system.
has super-classes
Questionnaire c
is in domain of
kingsValue dp

Labourers in mining, construction, manufacturing and transportc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C93

Labourers in mining, construction, manufacturing and transport perform simple and routine manual tasks in mining, quarrying, civil engineering, building, manufacturing, transport and storage operations, and operate human-powered and animal-drawn vehicles and machinery. Most occupations in this sub-major group require skills at the first ISCO skill level. Task performed by workers in this sub-major group usually include: digging holes and spreading excavated materials, sand, soil and gravel using hand-held tools; sorting, loading, unloading, moving, stacking and storing materials, equipment, products, supplies, baggage and cargo by hand; cleaning machinery, equipment, tools and work sites; packing and unpacking material and products and filling containers and shelves with products by hand; operating human-powered and animal-drawn vehicles and machinery. Occupations in this sub-major group are classified into the following minor groups: 931 Mining and Construction Labourers 932 Manufacturing Labourers 933 Transport and Storage Labourers
has super-classes
Occupation c
has members
Labourers in mining, construction, manufacturing and transport ni

lamotriginec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AX09

has super-classes
Pharmacologic Substance c
has members
n03 a x09 ni

Langerhans Cell Histiocytosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3107

has super-classes
Disease or Disorder c
has members
Langerhans Cell Histiocytosis ni
is also defined as
named individual

Legal, social and cultural professionalsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C26

Legal, social and cultural professionals conduct research; improve or develop concepts, theories and operational methods; or apply knowledge relating to the law, storage and retrieval of information and artefacts, psychology, social welfare, politics, economics, history, religion, languages, sociology, other social sciences, and arts and entertainment. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research on legal problems; drafting laws and regulations; advising clients on legal cases; pleading and conducting cases in a court of law; presiding over judicial proceedings in a court of law; developing and maintaining library and gallery collections of archives; conducting research, improving or developing concepts, theories and operational methods or applying knowledge relating to the field of social sciences; conceiving, creating and performing in literary and artistic works; interpreting and communicating news, ideas, impressions and facts. Occupations in this sub-major group are classified into the following minor groups: 261 Legal Professionals 262 Librarians, Archivists and Curators 263 Social and Religious Professionals 264 Authors, Journalists and Linguists 265 Creative and Performing Artists
has super-classes
Occupation c
has members
Legal, social and cultural professionals ni

Legal, social, cultural and related associate professionalsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C34

Legal, social, cultural and related associate professionals perform technical tasks connected with the practical application of knowledge relating to legal services, social work, culture, food preparation, sport and religion. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: providing technical and practical services and support functions in legal processes and investigations, social and community assistance programmes, and religious and cultural activities; participating and adjudicating in sporting events; developing and delivering sports coaching, fitness and recreational programmes; combining creative and technical skills in a variety of artistic, cultural and culinary activities; creating dishes and menus and overseeing the preparation of meals. Occupations in this sub-major group are classified into the following minor groups: 341 Legal, Social and Religious Associate Professionals 342 Sports and Fitness Workers 343 Artistic, Cultural and Culinary Associate Professionals
has super-classes
Occupation c
has members
Legal, social, cultural and related associate professionals ni

lercanidipinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C08CA13

has super-classes
Pharmacologic Substance c
has members
c08 c a13 ni

Leukopeniac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26816

has super-classes
Disease or Disorder c
has members
Leukopenia ni
is also defined as
named individual

levetiracetamc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AX14

has super-classes
Pharmacologic Substance c
has members
n03 a x14 ni

levodopa and decarboxylase inhibitorc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N04BA02

has super-classes
Pharmacologic Substance c
has members
n04 b a02 ni

levothyroxine sodiumc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/H03AA01

has super-classes
Pharmacologic Substance c
has members
h03 a a01 ni

Lifestylec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C16795

has super-classes
Personal Behavior c
is in domain of
diet dp, fatigue dp, female period start date dp, menopause dp, sexuality dp, sun exposure dp
is also defined as
named individual

Limbc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12429

has super-classes
anatomical structure c
has members
distal-left-limb ni, distal-left-right-limb ni, distal-limb ni, distal-proximal-left-limb ni, distal-proximal-left-right-limb ni, distal-proximal-limb ni, distal-proximal-right-limb ni, distal-right-limb ni, left-limb ni, left-right-limb ni, limb ni, lower-distal-left-limb ni, lower-distal-left-right-limb ni, lower-distal-limb ni, lower-distal-proximal-left-limb ni, lower-distal-proximal-left-right-limb ni, lower-distal-proximal-limb ni, lower-distal-proximal-right-limb ni, lower-distal-right-limb ni, lower-left-limb ni, lower-left-right-limb ni, lower-limb ni, lower-proximal-left-limb ni, lower-proximal-left-right-limb ni, lower-proximal-limb ni, lower-proximal-right-limb ni, lower-right-limb ni, proximal-left-limb ni, proximal-left-right-limb ni, proximal-limb ni, proximal-right-limb ni, right-limb ni, upper-distal-left-limb ni, upper-distal-left-right-limb ni, upper-distal-limb ni, upper-distal-proximal-left-limb ni, upper-distal-proximal-left-right-limb ni, upper-distal-proximal-limb ni, upper-distal-proximal-right-limb ni, upper-distal-right-limb ni, upper-left-limb ni, upper-left-right-limb ni, upper-limb ni, upper-lower-distal-left-limb ni, upper-lower-distal-left-right-limb ni, upper-lower-distal-limb ni, upper-lower-distal-proximal-left-limb ni, upper-lower-distal-proximal-left-right-limb ni, upper-lower-distal-proximal-limb ni, upper-lower-distal-proximal-right-limb ni, upper-lower-distal-right-limb ni, upper-lower-left-limb ni, upper-lower-left-right-limb ni, upper-lower-limb ni, upper-lower-proximal-left-limb ni, upper-lower-proximal-left-right-limb ni, upper-lower-proximal-limb ni, upper-lower-proximal-right-limb ni, upper-lower-right-limb ni, upper-proximal-left-limb ni, upper-proximal-left-right-limb ni, upper-proximal-limb ni, upper-proximal-right-limb ni, upper-right-limb ni
is also defined as
named individual

Lumbar Herniac back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Lumbar_Hernia

has super-classes
Hernia c
has members
Lumbar Hernia ni

lumbosacral nerve plexusc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0001815

An arrangement of nerve fibers, running from the spine that travels to the pelvic appendage where it innervates skin and muscle. [ http://purl.obolibrary.org/obo/UBERON_cjm ]
has super-classes
anatomical structure c
has members
lumbosacral nerve plexus ni

Lymphopeniac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26823

has super-classes
Disease or Disorder c
has members
Lymphopenia ni
is also defined as
named individual

Magnetic Resonance Imagingc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C16809

has super-classes
Diagnostic Imaging c
is in domain of
contiguousLesions dp, lesionsT1 dp, lesionsT1-Gadolinium dp, newOrEnlargedLesionsT2 dp, numberOfLesionsT1-Gadolinium dp, totalLesionsT2 dp
is also defined as
named individual

Malignant Skin Neoplasmc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2920

A primary or metastatic malignant neoplasm involving the skin. Primary malignant skin neoplasms most often are carcinomas (either basal cell or squamous cell carcinomas) or melanomas. Metastatic malignant neoplasms to the skin include carcinomas and lymphomas. [Definition Source: NCI]
has super-classes
Disease or Disorder c
has members
Malignant Skin Neoplasm ni

Market-oriented skilled agricultural workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C61

Market-oriented skilled agricultural workers plan, organize and perform farming operations to grow and harvest field or tree and shrub crops; and to produce a variety of animals and animal products for sale or delivery on a regular basis to wholesale buyers, marketing organizations or at markets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing the soil; sowing, planting, spraying, fertilizing and harvesting field crops; growing fruit and other tree and shrub crops; growing garden vegetables and horticultural products; raising, breeding and tending animals mainly to obtain meat, milk, hair, fur, skin, or sericultural, apiarian or other products; storing and carrying out some processing of produce; selling their products to purchasers, marketing organizations or at markets. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 611 Market Gardeners and Crop growers 612 Animal Producers 613 Mixed Crop and Animal Producers Notes Jobs should be classified in Sub-major Group 63: Subsistence Farmers, Fishers, Hunters and Gatherers when goods (mostly food) are produced mainly for own consumption or for consumption by other members of the worker’s household. If a large surplus is produced, and more goods are sold than consumed, but the main aim of production was own consumption, the jobs should nevertheless be classified in Sub-major Group 63. Jobs should only be classified in Sub-major Group 61: Market-oriented Skilled Agricultural Workers, or 62: Market-oriented Skilled Forestry, Fishery and Hunting Workers, if the main aim of the activity is to produce goods for the market.
has super-classes
Occupation c
has members
Market-oriented skilled agricultural workers ni

Market-oriented skilled forestry, fishery and hunting workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C62

Market-oriented skilled forestry, fishery and hunting workers plan, organize and perform operations to cultivate, conserve and exploit natural and plantation forests; breed and raise fish; harvest and catch fish; and hunt and trap animals, for sale or delivery on a regular basis to wholesale buyers, marketing organizations or at markets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: renting or investing in equipment and machinery and purchasing supplies; planning and undertaking forestry, aquaculture, fishery and hunting operations; maintaining buildings, tanks, machinery and other equipment; delivering or marketing products; supervising and training other workers. Occupations in this sub-major group are classified into the following minor groups: 621 Forestry and Related Workers 622 Fishery Workers, Hunters and Trappers Notes Jobs should be classified in Sub-major Group 63: Subsistence Farmers, Fishers, Hunters and Gatherers when goods (mostly food) are produced mainly for own consumption or for consumption by other members of the worker’s household. If a large surplus is produced, and more goods are sold than consumed, but the main aim of production was own consumption, the jobs should nevertheless be classified in Sub-major Group 63. Jobs should only be classified in Sub-major Group 61: Market-oriented Skilled Agricultural Workers, or 62: Market-oriented Skilled Forestry, Fishery and Hunting Workers, if the main aim of the activity is to produce goods for the market.
has super-classes
Occupation c
has members
Market-oriented skilled forestry, fishery and hunting workers ni

Melanocytic Nevusc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C7570

has super-classes
Disease or Disorder c
has members
Melanocytic Nevus ni
is also defined as
named individual

Metal, machinery and related trades workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C72

Metal, machinery and related trades workers cast, weld, forge and, by other methods, form metal; erect, maintain and repair heavy metal structures; engage in machine-tool setting as well as in fitting, maintaining and repairing machinery including engines and vehicles; or they produce tools and various non-precious metal articles. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product Tasks performed by workers in this sub-major group usually include: making moulds and cores for casting metal; casting, welding and shaping metal; installing, erecting, maintaining and repairing heavy metal structures, tackle and related equipment; forging and forming steel and other non-precious metals to make and repair machinery, tools, equipment and other articles; setting for operators or setting and operating various machine tools; fitting, maintaining and repairing industrial machinery, including engines and vehicles. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 721 Sheet and Structural Metal Workers, Moulders and Welders, and Related Workers 722 Blacksmiths, Toolmakers and Related Trades Workers 723 Machinery Mechanics and Repairers
has super-classes
Occupation c
has members
Metal, machinery and related trades workers ni

methotrexatec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L01BA01

has super-classes
Pharmacologic Substance c
has members
methotrexate ni

methylprednisolonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/D07AA01

has super-classes
Pharmacologic Substance c
has members
methylprednisolone ni

methylprednisolonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/H02AB04

has super-classes
Pharmacologic Substance c
has members
methylprednisolone ni

Migraine With Aurac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C117005

has super-classes
Disease or Disorder c
has members
Migraine With Aura ni
is also defined as
named individual

mirtazapinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06AX11

has super-classes
Pharmacologic Substance c
has members
n06 a x11 ni

Mitosc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Mitos

MiToS staging system.
has super-classes
Questionnaire c
is in domain of
mitosValue dp

mitoxantronec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L01DB07

has super-classes
Pharmacologic Substance c
has members
l01 d b07 ni

modafinilc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06BA07

has super-classes
Pharmacologic Substance c
has members
n06 b a07 ni

Monoclonal Gammopathyc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35548

has super-classes
Disease or Disorder c
has members
Monoclonal Gammopathy ni
is also defined as
named individual

Motherc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25189

has super-classes
First Degree Relative c
has members
Mother ni
is also defined as
named individual

multiple sclerosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/MONDO_0005301

has super-classes
Disease or Disorder c
has members
Multiple Sclerosis ni
is also defined as
named individual

Mumpsc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C29888

A contagious viral infection caused by the mumps virus. Symptoms include swollen and tender parotid glands, fever, muscle aches and fatigue. Due to vaccination programs, mumps has become a rare disease. [Definition Source: NCI]
has super-classes
Disease or Disorder c
has members
Mumps ni

Myasthenia Gravisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C60989

has super-classes
Disease or Disorder c
has members
Myasthenia Gravis ni
is also defined as
named individual

n c i t c3390c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3390

is equivalent to
stroke c

naltrexonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N07BB04

has super-classes
Pharmacologic Substance c
has members
naltrexone ni

natalizumabc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L04AA23

has super-classes
Pharmacologic Substance c
has members
natalizumab ni

nebivololc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C07AB12

has super-classes
Pharmacologic Substance c
has members
c07 a b12 ni

neckc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0000974

An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column. [ http://orcid.org/0000-0002-6601-2165 ]
has super-classes
anatomical structure c
has members
neck ni

Neonatal Hearing Impairmentc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50667

has super-classes
Disease or Disorder c
has members
Neonatal Hearing Impairment ni
is also defined as
named individual

Neoplasiac back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Neoplasia

Phenotype that consists of abnormal growth of a tissue or organ due to increased numbers of cells, but in which the affected tissue or organ does not maintain its normal form. Excluding the non-melanoma skin cancer (NMSC).
has super-classes
Disease or Disorder c
has members
Neoplasia ni

Nephewc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71409

has super-classes
Second Degree Relative c
has members
Nephew ni
is also defined as
named individual

Nervous System Findingc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C36280

has super-classes
Symptom c
has members
Nervous System Finding ni
is also defined as
named individual

Niecec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71408

has super-classes
Second Degree Relative c
has members
Niece ni
is also defined as
named individual

NMSCc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/NMSC

Nonmelanoma Skin Cancers
has super-classes
Disease or Disorder c
has members
NMSC ni

Non-commissioned armed forces officersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C02

Non-commissioned armed forces officers enforce military discipline and supervise the activities of those employed in Sub-major Group 03: Armed Forces Occupations, Other Ranks, and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. This group includes members of the armed forces holding ranks such as sergeant, warrant officer and sergeant major. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 021 Non-commissioned Armed Forces Officers Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.
has super-classes
Occupation c
has members
Non-commissioned armed forces officers ni

Non-Invasive Mechanical Ventilationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C171457

has super-classes
Therapeutic Procedure c
has members
Non-Invasive Mechanical Ventilation ni
is also defined as
named individual

Numerical and material recording clerksc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C43

Numerical and material recording clerks obtain, compile and compute accounting, bookkeeping, statistical, financial and other numerical data, and take charge of cash transactions incidental to business matters. Some occupations classified here keep records of goods produced, purchased, stocked and dispatched, and of materials needed at specified production dates, or keep records of operational aspects and coordinate the timing of passenger and freight transport. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: helping with accounting and bookkeeping records and computations; calculating unit production costs; calculating wages and in some cases preparing wage packets and paying wages; taking charge of cash transactions incidental to the business; obtaining, compiling and computing statistical or actuarial data; performing clerical tasks relating to the financial transactions of an insurance establishment, bank or similar establishment; recording produced, stocked, ordered and dispatched goods; recording production materials received, put into stock or issued; computing quantities of the production materials required at specified dates and helping with preparation and checking of production operation schedules; keeping records of operational aspects and coordinating the timing of passenger and freight transport. Occupations in this sub-major group are classified into the following minor groups: 431 Numerical Clerks 432 Material Recording and Transport Clerks
has super-classes
Occupation c
has members
Numerical and material recording clerks ni

Obesityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3283

has super-classes
Disease or Disorder c
has members
Obesity ni
is also defined as
named individual

Occupationc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/model#Occupation

The principal activity that a person does to earn money. [Definition Source: NCI]
has sub-classes
Administrative and commercial managers c, Agricultural, forestry and fishery labourers c, Armed forces occupations, other ranks c, Assemblers c, Building and related trades workers, excluding electricians c, Business and administration associate professionals c, Business and administration professionals c, Chief executives, senior officials and legislators c, Cleaners and helpers c, Commissioned armed forces officers c, Customer services clerks c, Drivers and mobile plant operators c, Electrical and electronic trades workers c, Elementary occupations c, Food preparation assistants c, Food processing, wood working, garment and other craft and related trades workers c, General and keyboard clerks c, Handicraft and printing workers c, Health associate professionals c, Health professionals c, Hospitality, retail and other services managers c, Information and communications technicians c, Information and communications technology professionals c, Labourers in mining, construction, manufacturing and transport c, Legal, social and cultural professionals c, Legal, social, cultural and related associate professionals c, Market-oriented skilled agricultural workers c, Market-oriented skilled forestry, fishery and hunting workers c, Metal, machinery and related trades workers c, Non-commissioned armed forces officers c, Numerical and material recording clerks c, Other clerical support workers c, Personal care workers c, Personal service workers c, Production and specialised services managers c, Protective services workers c, Refuse workers and other elementary workers c, Sales workers c, Science and engineering associate professionals c, Science and engineering professionals c, Stationary plant and machine operators c, Street and related sales and service workers c, Subsistence farmers, fishers, hunters and gatherers c, Teaching professionals c
is in range of
hasOccupation op
has members
Occupation ni

ocrelizumabc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L04AA36

has super-classes
Pharmacologic Substance c
has members
l04 a a36 ni

olmesartan medoxomilc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C09CA08

has super-classes
Pharmacologic Substance c
has members
c09 c a08 ni

Onsetc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25279

has super-classes
Event c
is in domain of
age_onset dp, axial dp, bulbar dp, cerebrospinalOligloconalBands dp, generalized dp, limbs dp, site op
is also defined as
named individual

Osteoporosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3298

has super-classes
Disease or Disorder c
has members
Osteoporosis ni
is also defined as
named individual

Other clerical support workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C44

Other clerical support workers sort and deliver mail, file documents, prepare information for processing, maintain personnel records, check material for consistency with original source material, assist persons who cannot read or write, and perform various other specialized clerical duties. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: recording information regarding acquisition, issue and return of library books; classifying and filing various documents and other records; maintaining personnel records; sorting, recording and delivering mail from post offices, as well as from or within an enterprise; coding; correcting proofs; performing a range of miscellaneous clerical duties; writing on behalf of persons who are unable to read or write. Occupations in this sub-major group are classified into the following minor group: 441 Other Clerical Support Workers
has super-classes
Occupation c
has members
Other clerical support workers ni

Other viral vaccines in ATCc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/J07BX

has super-classes
Pharmacologic Substance c
has members
j07 b x ni

oxcarbazepinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AF02

has super-classes
Pharmacologic Substance c
has members
n03 a f02 ni

oxybutyninc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/G04BD04

has super-classes
Pharmacologic Substance c
has members
g04 b d04 ni

paliperidonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N05AX13

has super-classes
Pharmacologic Substance c
has members
n05 a x13 ni

paroxetinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06AB05

has super-classes
Pharmacologic Substance c
has members
n06 a b05 ni

Partial Epilepsyc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C122812

has super-classes
Symptom c
has members
Partial Epilepsy ni
is also defined as
named individual

Patientc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C16960

A person who receives medical attention, care, or treatment, or who is registered with medical professional or institution with the purpose to receive medical care when necessary. [Definition Source: NCI]
is equivalent to
c0030705 c
has super-classes
Person c
is in domain of
MSInPaediatricAge dp, alive dp, dateOfDeath dp, deathDueToALS dp, dextricity dp, educationLevel dp, ethnicity op, genomeSequencing dp, hasGene op, hasOccupation op, hasRelative op, maritalStatus dp, menopause dp, notes dp, retiredAtDiagnosis dp, undergo op, yearOfDeath dp

Patient Visitc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C39564

has super-classes
Protocol Event c
is also defined as
named individual

peginterferon beta-1ac back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L03AB13

has super-classes
Pharmacologic Substance c
has members
l03 a b13 ni

pelvic complexc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0010709

Appendage girdle complex that when present, encompasses the pelvic appendicular skeleton and the pelvic girdle. [ VSAO:0000215 ]
has super-classes
anatomical structure c
has members
pelvic complex ni

Penicillin Allergyc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34911

has super-classes
Disease or Disorder c
has members
Penicillin Allergy ni
is also defined as
named individual

Percutaneous Endoscopic Gastrostomyc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C106040

has super-classes
Surgical Procedure c
has members
Percutaneous Endoscopic Gastrostomy ni
is also defined as
named individual

perindopril and amlodipinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C09BB04

has super-classes
Pharmacologic Substance c
has members
c09 b b04 ni

Personc back to ToC or Class ToC

IRI: http://www.w3.org/2000/10/swap/pim/contact#Person

A person.
has sub-classes
Patient c
is in domain of
enrolledIn op, hasBirthplace op, hasDisease op, hasResidence op, sex dp, yearOfBirth dp
is in range of
isPerson op
has members
Gianmaria Silvello ni, Giorgio Maria Di Nunzio ni, Guglielmo Faggioli ni, Manuel Bettin ni, Nicola Ferro ni, Nicola Marchetti ni

Personal care workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C53

Personal care workers provide care, supervision and assistance for children, patients and elderly, convalescent or disabled persons in institutional and residential settings. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: assisting with mobility, washing and other personal needs; assisting children individually to learn social skills; supervising and participating in activities that enhance children’s physical, social, emotional and intellectual development; observing and reporting concerns to appropriate health or social service workers. Occupations in this sub-major group are classified into the following minor groups: 531 Child Care Workers and Teachers’ Aides 532 Personal Care Workers in Health Services
has super-classes
Occupation c
has members
Personal care workers ni

Personal service workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C51

Personal services workers provide personal services related to travel, housekeeping, catering and hospitality, hairdressing and beauty treatment, animal care grooming and training, companionship and other services of a personal nature. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: organizing and providing services in connection with travel and sightseeing; housekeeping; preparing and serving food and beverages; hairdressing and beauty treatment; telling fortunes; embalming and arranging funerals; grooming, caring for and training animals; teaching people to drive motor vehicles; providing companionship and other personal services. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 511 Travel Attendants, Conductors and Guides 512 Cooks 513 Waiters and Bartenders 514 Hairdressers, Beauticians and Related Workers 515 Building and Housekeeping Supervisors 516 Other Personal Services Workers
has super-classes
Occupation c
has members
Personal service workers ni

Personality Disorderc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34922

has super-classes
Disease or Disorder c
has members
Personality Disorder ni
is also defined as
named individual

phenobarbitalc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AA02

has super-classes
Pharmacologic Substance c
has members
n03 a a02 ni

Physical Activityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C17708

has super-classes
Personal Behavior c
is in domain of
activityType dp, intensity dp, weeklyFrequence dp
is also defined as
named individual

Pituitary Gland Adenomac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3329

has super-classes
Disease or Disorder c
has members
Pituitary Gland Adenoma ni
is also defined as
named individual

Pneumococcal Pneumoniac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C157959

has super-classes
Disease or Disorder c
has members
Pneumococcal Pneumonia ni
is also defined as
named individual

Positron Emission Tomographyc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C17007

has super-classes
Diagnostic Imaging c
is also defined as
named individual

Postoperative Hypothyroidismc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Postoperative_Hypothyroidism

has super-classes
Hypothyroidism c
has members
Postoperative Hypothyroidism ni

pramipexolec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N04BC05

has super-classes
Pharmacologic Substance c
has members
n04 b c05 ni

prasugrelc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/B01AC22

has super-classes
Pharmacologic Substance c
has members
b01 a c22 ni

prazepamc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N05BA11

has super-classes
Pharmacologic Substance c
has members
n05 b a11 ni

prednisonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/H02AB07

has super-classes
Pharmacologic Substance c
has members
h02 a b07 ni

pregabalinc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AX16

has super-classes
Pharmacologic Substance c
has members
n03 a x16 ni

Primary Neoplasmc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C8509

has super-classes
Disease or Disorder c
has members
Primary Neoplasm ni
is also defined as
named individual

Production and specialised services managersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C13

Production and specialized services managers plan, direct and coordinate the production of the goods and the provision of the specialized professional and technical services provided by an enterprise or organization, either as the manager of a department or as the general manager of an enterprise or organization that does not have a hierarchy of managers. They are responsible for manufacturing, mining, construction, logistics, information and communications technology operations for large-scale agricultural, forestry and fisheries operations, and for the provision of health, education, social welfare, banking, insurance and other professional and technical services. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: planning details of activities in terms of output, services provided, quality, quantity, cost, timeliness and labour requirements; setting standards and objectives; controlling the operation of plant and of procedures; assuring quality of the goods produced and services provided; preparing tenders and contract bids; establishing and managing budgets, monitoring costs, and adjusting activities, procedures and resources to minimize costs; overseeing the acquisition and installation of new plant and equipment; coordinating the implementation of health and safety requirements; planning and directing daily operations; overseeing the selection, training and performance of staff; preparing, or arranging for the preparation of, reports, budgets and forecasts; representing the enterprise or organization in negotiations with other agencies, and at conventions, seminars, public hearings and forums. Occupations in this sub-major group are classified into the following minor groups: 131 Production Managers in Agriculture, Forestry and Fisheries 132 Manufacturing, Mining, Construction and Distribution Managers 133 Information and Communications Technology Services Managers 134 Professional Services Managers Note Specialized qualifications and extensive experience relevant to one or more occupations classified in Major Group 2: Professionals, or Major Group 3: Technicians and Associate Professionals, are usually required. Regional managers and other senior managers who coordinate and supervise the activities of subordinate managers who have a diverse range of functional responsibilities are included in Unit Group 1120: Managing Directors and Chief Executives.
has super-classes
Occupation c
has members
Production and specialised services managers ni

propranololc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C07AA05

has super-classes
Pharmacologic Substance c
has members
c07 a a05 ni

Protective services workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C54

Protective services workers protect individuals and property against fire and other hazards, maintain law and order and enforce laws and regulations. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preventing, fighting and extinguishing fires; rescuing people from burning buildings and accident sites and those trapped in dangerous situations; maintaining law and order, enforcing laws and regulations, patrolling public areas and arresting suspected offenders; directing traffic and assuming authority in the event of accidents; watching over and maintaining order among inmates of prisons, reformatories or penitentiaries; patrolling or monitoring premises to guard property against theft and vandalism, controlling access to establishments and maintaining order and enforcing regulations at public events and within establishments. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor group: 541 Protective Services Workers
has super-classes
Occupation c
has members
Protective services workers ni

Protocol Eventc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C74589

has super-classes
Event c
has sub-classes
Patient Visit c
is also defined as
named individual

Psoriasisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3346

has super-classes
Disease or Disorder c
has members
Psoriasis ni
is also defined as
named individual

Pulmonary Embolismc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50713

has super-classes
Disease or Disorder c
has members
Pulmonary Embolism ni
is also defined as
named individual

Pulmonary Function Testc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C38081

has super-classes
Diagnostic Procedure c
is in domain of
AOPabsolute dp, AOPrelative dp, FVCabsolute dp, FVCrelative dp, MEPabsolute dp, MEPrelative dp, MIPabsolute dp, MIPrelative dp, PCO2 dp, PO2 dp, VCabsolute dp, VCrelative dp
is also defined as
named individual

Pulmonary Sarcoidosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34997

has super-classes
Disease or Disorder c
has members
Pulmonary Sarcoidosis ni
is also defined as
named individual

Pulmonary Thromboembolismc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Pulmonary_Thromboembolism

has super-classes
Thromboembolism c
has members
Pulmonary Thromboembolism ni

Pyramidal Symptomc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Pyramidal_Symptom

has super-classes
Symptom c
has members
Pyramidal Symptom ni

Questionnairec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C17048

has super-classes
Diagnostic Procedure c
has sub-classes
ALSFRS c, ALSFRS-R c, Kings c, Mitos c
is also defined as
named individual

ramiprilc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C09AA05

has super-classes
Pharmacologic Substance c
has members
c09 a a05 ni

Refuse workers and other elementary workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C96

Refuse workers and other elementary workers collect, process and recycle garbage from buildings, yards, streets and other public places. They keep streets and other public places clean and tidy, deliver and carry messages and packages and perform odd jobs for private households or establishments. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: collecting, loading and unloading garbage; sweeping streets, parks and other public places; chopping firewood; collecting and carrying firewood, water, packages, luggage and messages; beating dust out of carpets and performing other odd-job tasks. Occupations in this sub-major group are classified into the following minor groups: 961 Refuse Workers 962 Other Elementary Workers
has super-classes
Occupation c
has members
Refuse workers and other elementary workers ni

Renal Colicc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C78593

has super-classes
Disease or Disorder c
has members
Renal Colic ni
is also defined as
named individual

Retinal Detachmentc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26874

An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision. [Definition Source: NCI]
has super-classes
Disease or Disorder c
has members
Retinal Detachment ni

Rheumatoid Arthritisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2884

has super-classes
Disease or Disorder c
has members
Rheumatoid Arthritis ni
is also defined as
named individual

riluzolec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N07XX02

has super-classes
Pharmacologic Substance c
has members
riluzole ni

rituximabc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L01XC02

has super-classes
Pharmacologic Substance c
has members
l01 x c02 ni

rivaroxabanc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/B01AF01

has super-classes
Pharmacologic Substance c
has members
b01 a f01 ni

rivastigminec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06DA03

has super-classes
Pharmacologic Substance c
has members
n06 d a03 ni

rural areac back to ToC or Class ToC

IRI: https://uts.nlm.nih.gov/uts/umls/concept/C0178837

area outside of cities and towns. (CSP)
has super-classes
Place c
has members
rural area ni

Sales workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C52

Sales workers sell and demonstrate goods in wholesale or retail shops, at stalls and markets, door-to-door, via telephone or customer contact centres. They may record and accept payment for goods and services purchased, and may operate small retail outlets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: selling goods in wholesale or retail establishments, at street or market stalls, door-to-door, via telephone or customer contact centres; demonstrating and displaying goods to potential customers; selling and serving food for immediate consumption at counters and in the street; buying or contracting a regular supply of products to be sold; stacking and displaying goods for sale and wrapping or packing goods sold; determining product mix, stock and price levels for goods to be sold; operating cash registers, optical price scanners, computers or other equipment to record and accept payment for the purchase of goods and services. Supervision of other workers may be required in some occupations classified here. Occupations in this sub-major group are classified into the following minor groups: 521 Street and Market Salespersons 522 Shop Salespersons 523 Cashiers and Ticket Clerks 524 Other Sales Workers Note Shop managers and sales managers are classified in Major Group 1: Managers. Technical, medical and information and communications technology sales professionals are classified in Major Group 2: Professionals. Commercial sales and insurance representatives, finance and trade brokers, are classified in Major Group 3: Technicians and Associate Professionals. Street vendors (excluding food) are classified in Major Group 9: Elementary Occupations.
has super-classes
Occupation c
has members
Sales workers ni

Scarlet Feverc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C94575

has super-classes
Disease or Disorder c
has members
Scarlet Fever ni
is also defined as
named individual

Science and engineering associate professionalsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C31

Science and engineering associate professionals perform technical tasks connected with research and operational methods in science and engineering. They supervise and control technical and operational aspects of mining, manufacturing, construction and other engineering operations, and operate technical equipment including aircraft and ships. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: setting up, monitoring and operating instruments and equipment, conducting and monitoring experiments and tests of systems; collecting and testing samples; recording observations and analysing data; preparing, revising and interpreting technical drawings and diagrams; coordinating, supervising, controlling and scheduling the activities of other workers; operating and monitoring switchboards, computerized control systems, and multi-function process control machinery; performing technical functions to ensure safe and efficient movement and operations in ships, aircraft and other equipment. Occupations in this sub-major group are classified into the following minor groups: 311 Physical and Engineering Science Technicians 312 Mining, Manufacturing and Construction Supervisors 313 Process Control Technicians 314 Life Science Technicians and Related Associate Professionals 315 Ship and Aircraft Controllers and Technicians
has super-classes
Occupation c
has members
Science and engineering associate professionals ni

Science and engineering professionalsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C21

Science and engineering professionals conduct research; improve or develop concepts, theories and operational methods; or apply scientific knowledge relating to fields such as physics, astronomy, meteorology, chemistry, geophysics, geology, biology, ecology, pharmacology, medicine, mathematics, statistics, architecture, engineering, design and technology. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research, enlarging, advising on or applying scientific knowledge obtained through the study of structures and properties of physical matter and phenomena, chemical characteristics and processes of various substances, materials and products, all forms of human, animal and plant life and of mathematical and statistical concepts and methods; advising on, designing and directing construction of buildings, towns and traffic systems, or civil engineering and industrial structures, as well as machines and other equipment; advising on and applying mining methods and ensuring their optimum use; surveying land and sea and making maps; studying and advising on technological aspects of particular materials, products and processes, and on efficiency of production and work organization; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 211 Physical and Earth Science Professionals 212 Mathematicians, Actuaries and Statisticians 213 Life Science Professionals 214 Engineering Professionals (excluding Electrotechnology) 215 Electrotechnology Engineers 216 Architects, Planners, Surveyors and Designers
has super-classes
Occupation c
has members
Science and engineering professionals ni

Second Degree Relativec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C19811

has super-classes
Relative c
has sub-classes
Grandchild c, Nephew c, Niece c
has members
Second Degree Relative ni
is also defined as
named individual

Seizure Disorderc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3020

has super-classes
Disease or Disorder c, Symptom c
has members
Seizure Disorder ni
is also defined as
named individual

Sensory Disorderc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C63711

has super-classes
Symptom c
has members
Sensory Disorder ni
is also defined as
named individual

sertralinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06AB06

has super-classes
Pharmacologic Substance c
has members
n06 a b06 ni

Serum Glutamic Pyruvic Transaminase, CTCAEc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C55098

has super-classes
Disease or Disorder c
has members
Serum Glutamic Pyruvic Transaminase, CTCAE ni
is also defined as
named individual

Shoulder Dislocationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35020

has super-classes
Disease or Disorder c
has members
Shoulder Dislocation ni
is also defined as
named individual

Siblingc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25204

has super-classes
Relative c
has sub-classes
Brother c, Sister c
has members
Sibling ni
is also defined as
named individual

siponimodc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L04AA42

has super-classes
Pharmacologic Substance c
has members
l04 a a42 ni

Sisterc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25680

has super-classes
Sibling c
has members
Sister ni
is also defined as
named individual

sitagliptinc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/A10BH01

has super-classes
Pharmacologic Substance c
has members
a10 b h01 ni

Sjogren Syndromec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26883

has super-classes
Disease or Disorder c
has members
Sjogren Syndrome ni
is also defined as
named individual

Smokingc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C154329

has super-classes
Personal Behavior c
is in domain of
before20Years dp, dailyCigarettes dp, packYear dp
has members
Smoking ni
is also defined as
named individual

SOD1c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OGG_3000006647

This gene plays a role in the detoxification of superoxide radicals in the cytosol. [Definition Source: NCI]
has super-classes
gene c
has members
SOD1 ni

Sonc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25205

has super-classes
First Degree Relative c
has members
Son ni
is also defined as
named individual

Spinal Cordc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0002240

has super-classes
anatomical structure c
has members
Spinal Cord ni
is also defined as
named individual

Spinal Cord Symptomc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Spinal_Cord_Symptom

has super-classes
Symptom c
has members
Spinal Cord Symptom ni

Stationary plant and machine operatorsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C81

Stationary plant and machine operators monitor and operate stationary industrial plant, machinery and equipment, or for which mobility is not an integral part of operation. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work mainly calls for experience with and an understanding of the industrial plant, machinery or equipment being operated and monitored. Ability to cope with machine-paced operations and to adapt to innovations in machinery and equipment are often required. Tasks performed by workers in this sub-major group usually include: setting up, operating and monitoring a variety of stationary plant and machinery; detecting malfunctions and taking corrective action; examining outputs for defects and conformity with specifications and adjusting machine settings accordingly; performing maintenance, repairs and cleaning; recording data and maintaining production records. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 811 Mining and Mineral Processing Plant Operators 812 Metal Processing and Finishing Plant Operators 813 Chemical and Photographic Products Plant and Machine Operators 814 Rubber, Plastic and Paper Products Machine Operators 815 Textile, Fur and Leather Products Machine Operators 816 Food and Related Products Machine Operators 817 Wood Processing and Papermaking Plant Operators 818 Other Stationary Plant and Machine Operators Note Operators of machinery that involves automated control of multiple processes or functions are included in Minor Group 313: Process Control Technicians.
has super-classes
Occupation c
has members
Stationary plant and machine operators ni

Street and related sales and service workersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C95

Street and related sales and services workers sell goods (excluding food) for immediate consumption, and provide a variety of services on streets and in other public places such as stations. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: buying or making various items for sale; loading and unloading items for sale and transporting them; obtaining the materials necessary to perform services; approaching people on the street to offer goods or services; cleaning and polishing shoes; cleaning and polishing car windows; running errands; assisting car drivers to find a parking place and ensuring that the car is not damaged during the driver’s absence; handing out leaflets and free newspapers; receiving immediate payment. Occupations in this sub-major group are classified into the following minor groups: 951 Street and Related Services Workers 952 Street Vendors (excluding Food)
has super-classes
Occupation c
has members
Street and related sales and service workers ni

strokec back to ToC or Class ToC

IRI: http://www.ebi.ac.uk/efo/EFO_0000712

has super-classes
Disease or Disorder c
has members
stroke ni
is also defined as
named individual

Subsistence farmers, fishers, hunters and gatherersc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C63

Subsistence farmers, fishers, hunters and gatherers grow and harvest field or tree and shrub crops, vegetables and fruit; gather wild fruits, medicinal and other plants; tend or hunt animals; catch fish and gather various forms of aquatic life in order to provide food, shelter and, in some cases, a minimum of cash income for themselves and their households. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing the soil; sowing, planting, tending and harvesting field crops; growing vegetables, fruit and other tree and shrub crops; gathering wild fruits, medicinal and other plants; breeding, tending and feeding animals and poultry mainly to obtain meat, eggs, milk, hair, skin or other products; hunting or trapping animals; catching fish and gathering other forms of aquatic life; fetching water and gathering firewood; storing produce for later use and carrying out some processing of produce; building and maintaining houses and other shelters; making tools, clothes and utensils for use by the household; selling or bartering some products at local markets. Occupations in this sub-major group are classified into the following minor groups: 631 Subsistence Crop Farmers 632 Subsistence Livestock Farmers 633 Subsistence Mixed Crop and Livestock Farmers 634 Subsistence Fishers, Hunters, Trappers and Gatherers Notes Jobs should be classified in Sub-major Group 63: Subsistence Farmers, Fishers, Hunters and Gatherers when goods (mostly food) are produced mainly for own consumption or for consumption by other members of the worker’s household. If a large surplus is produced, and more goods are sold than consumed, but the main aim of production was for own consumption, the jobs should nevertheless be classified in Sub-major Group 63. Jobs should only be classified in Sub-major Group 61: Market-oriented Skilled Agricultural Workers, or 62: Market-oriented Skilled Forestry, Fishery and Hunting Workers, if the main aim of the activity is to produce goods for the market. Jobs are also classified in Sub-major Group 63 when goods are produced only for own consumption or for consumption by members of the worker’s household, and no cash income or bartering is involved.
has super-classes
Occupation c
has members
Subsistence farmers, fishers, hunters and gatherers ni

sulfasalazinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/A07EC01

has super-classes
Pharmacologic Substance c
has members
a07 e c01 ni

Supratentorial Symptomc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Supratentorial_Symptom

has super-classes
Symptom c
has members
Supratentorial Symptom ni

Surgical Procedurec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15329

has super-classes
Intervention or Procedure c
has sub-classes
CSF Analysis c, Percutaneous Endoscopic Gastrostomy c, Tracheotomy c
is in domain of
surgicalArea op
has members
Surgical Interventions Before Onset ni, Surgical Procedure ni
is also defined as
named individual

Symptomatic Therapyc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C170740

Therapy that treats adverse events without addressing the basic cause of those adverse events. [Definition Source: NCI]
has super-classes
Therapeutic Procedure c

Syncopec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35053

has super-classes
Disease or Disorder c
has members
Syncope ni
is also defined as
named individual

tamoxifenc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L02BA01

has super-classes
Pharmacologic Substance c
has members
l02 b a01 ni

TARDBPc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OGG_3000023435

This gene is involved in transcription and mRNA splicing. [Definition Source: NCI]
has super-classes
gene c
has members
TARDBP ni

Teaching professionalsc back to ToC or Class ToC

IRI: http://data.europa.eu/esco/isco/C23

Teaching professionals teach the theory and practice of one or more disciplines at different educational levels; conduct research; improve or develop concepts, theories and operational methods pertaining to their particular discipline; and prepare scholarly papers and books. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting classes, courses, or tutorials at a particular educational level for educational and vocational purposes, including private lessons; conducting adult literacy programmes; teaching and educating persons with learning difficulties or special needs; designing and modifying curricula; inspecting and advising on teaching methods and aids; participating in decisions concerning the organization of teaching and related activities at schools and universities; conducting research in particular subjects to improve or develop concepts, theories or operational methods for application in industrial and other fields; preparing scholarly papers and books. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor group: 231 University and Higher Education Teachers 232 Vocational Education Teachers 233 Secondary Education Teachers 234 Primary School and Early Childhood Teachers 235 Other Teaching Professionals
has super-classes
Occupation c
has members
Teaching professionals ni

telmisartanc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/C09CA07

has super-classes
Pharmacologic Substance c
has members
c09 c a07 ni

teriflunomidec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/L04AA31

has super-classes
Pharmacologic Substance c
has members
l04 a a31 ni

tetracosactidec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/H01AA02

has super-classes
Pharmacologic Substance c
has members
h01 a a02 ni

Thalassemiac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35069

has super-classes
Disease or Disorder c
has members
Thalassemia ni
is also defined as
named individual

Therapeutic Procedurec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C49236

has super-classes
Intervention or Procedure c
has sub-classes
Disease Modifying Therapy c, Non-Invasive Mechanical Ventilation c, Symptomatic Therapy c
is in domain of
hasAdministration op
is in range of
employs op
is also defined as
named individual

thiamazolec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/H03BB02

has super-classes
Pharmacologic Substance c
has members
h03 b b02 ni

thoracic skeletonc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0014477

Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum. [ http://en.wikipedia.org/wiki/Rib_cage https://orcid.org/0000-0002-6601-2165 ]
has super-classes
anatomical structure c
has members
thoracic skeleton ni

thoracic spinal cordc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/UBERON_0003038

has super-classes
anatomical structure c
has members
thoracic spinal cord ni
is also defined as
named individual

Thromboembolismc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C28195

has super-classes
Disease or Disorder c
has sub-classes
Pulmonary Thromboembolism c
has members
Thromboembolism ni
is also defined as
named individual

Thyroid Gland Disorderc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26893

has super-classes
Disease or Disorder c
has members
Thyroid Gland Disorder ni
is also defined as
named individual

Thyroiditisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26894

Inflammation of the thyroid gland. This category includes Hashimoto thyroiditis, Riedel thyroiditis, acute thyroiditis, subacute thyroiditis, and radiation-induced thyroiditis. [Definition Source: NCI]
has super-classes
Disease or Disorder c
has members
Thyroiditis ni

ticlopidinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/B01AC05

has super-classes
Pharmacologic Substance c
has members
b01 a c05 ni

tizanidinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/M03BX02

has super-classes
Pharmacologic Substance c
has members
m03 b x02 ni

Tomography, Optical Coherencec back to ToC or Class ToC

IRI: https://uts.nlm.nih.gov/uts/umls/concept/C0920367

An imaging method using LASERS that is used for mapping subsurface structure. When a reflective site in the sample is at the same optical path length (coherence) as the reference mirror, the detector observes interference fringes. (MSH)
has super-classes
Diagnostic Imaging c
is in domain of
octValue dp

topiramatec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AX11

has super-classes
Pharmacologic Substance c
has members
n03 a x11 ni

Townsc back to ToC or Class ToC

IRI: https://uts.nlm.nih.gov/uts/umls/concept/C0557750

Human settlements larger than a village but smaller than a city. (MSH)
has super-classes
Place c
has members
Towns ni

Tracheotomyc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15341

has super-classes
Surgical Procedure c
has members
Tracheotomy ni
is also defined as
named individual

Transient Ischemic Attackc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50781

has super-classes
Disease or Disorder c
has members
Transient Ischemic Attack ni
is also defined as
named individual

trazodonec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06AX05

has super-classes
Pharmacologic Substance c
has members
n06 a x05 ni

trospiumc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/G04BD09

has super-classes
Pharmacologic Substance c
has members
trospium ni

Type 1 Diabetes Mellitusc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2986

has super-classes
Diabetes Mellitus c
has members
Type 1 Diabetes Mellitus ni
is also defined as
named individual

Type 2 Diabetes Mellitusc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26747

has super-classes
Diabetes Mellitus c
has members
Type 2 Diabetes Mellitus ni
is also defined as
named individual

Unclec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71404

has super-classes
Relative c
has members
Uncle ni
is also defined as
named individual

valproic acidc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AG01

has super-classes
Pharmacologic Substance c
has members
n03 a g01 ni

venlafaxinec back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N06AX16

has super-classes
Pharmacologic Substance c
has members
n06 a x16 ni

Vertebral Herniac back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Vertebral_Hernia

has super-classes
Hernia c
has members
Vertebral Hernia ni

vigabatrinc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N03AG04

has super-classes
Pharmacologic Substance c
has members
n03 a g04 ni

warfarinc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/B01AA03

has super-classes
Pharmacologic Substance c
has members
b01 a a03 ni

zolpidemc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N05CF02

has super-classes
Pharmacologic Substance c
has members
n05 c f02 ni

zuclopenthixolc back to ToC or Class ToC

IRI: http://purl.bioontology.org/ontology/ATC/N05AF05

has super-classes
Pharmacologic Substance c
has members
n05 a f05 ni

Object Properties

areaop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/area

The area of diagnostic imaging.
has domain
Diagnostic Imaging c
has range
anatomical structure c

associatedSubstanceop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/associatedSubstance

When something of interest is associated to a pharmaceutic substance.

consistsop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/consists

An event consists of an intervention or procedure.
has domain
Event c
has range
Intervention or Procedure c

determinedByop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/determinedBy

A comorbidity determined by a disease or disorder.
has domain
Comorbidity c
has range
Disease or Disorder c

employsop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/employs

When a disease, which might be related to a comorbidity, employs a particular therapeutic procedure.

enrolledInop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/enrolledIn

A person enrolled in a clinical trial participation.
has domain
Person c
has range
Clinical Trial Participation c

ethnicityop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ethnicity

The ethnicity of a patient.

has characteristics: functional

has domain
Patient c
has range
Ethnic group c

hasAdministrationop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasAdministration

When a therapeutic procedure involves the administration of pharmacologic substances.
has domain
Therapeutic Procedure c
has range
Administration c

hasAssociatedPregnancyop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasAssociatedPregnancy

When a relapse is related to a pregnancy.

hasBirthplaceop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasBirthplace

The birthplace of a person.
has domain
Person c
has range
Place c

hasDiseaseop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasDisease

A person has a disease or disorder.
has domain
Person c
has range
Disease or Disorder c

hasGeneop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasGene

A patient has a gene.
has domain
Patient c
has range
gene c

hasOccupationop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasOccupation

A patient has an occupation.

has characteristics: functional

has domain
Patient c
has range
Occupation c

hasPregnancyop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasPregnancy

An event that consists in a pregnancy.
has domain
Event c
has range
Pregnancy c

hasRegisteredBehaviourop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasRegisteredBehaviour

An event has a registered behaviour.
has domain
Event c
has range
Personal Behavior c

hasRegisteredComorbidityop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasRegisteredComorbidity

An event has a registered comorbidity.
has domain
Event c
has range
Comorbidity c

hasRelapseop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasRelapse

State that an event consists on a relapse.
has domain
Event c
has range
Recurrent Disease c

hasRelativeop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasRelative

A patient has a relative with observed disease.
has domain
Patient c
has range
Relative c

hasResidenceop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasResidence

The residence of a person.
has domain
Person c
has range
Place c

hasSymptomop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasSymptom

An event is associated to a symptom.
has domain
Event c
has range
Symptom c

hasTraumaop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasTrauma

An event has a registered trauma.
has domain
Event c
has range
Injury c

isAboutDiseaseop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/isAboutDisease

A clinical trial is about disease or disorder.
has domain
Clinical Trial c
has range
Disease or Disorder c

isPersonop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/isPerson

A relative is a person.
has domain
Relative c
has range
Person c

isRelatedop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/isRelated

An administration regards a pharmacologic substance.
has domain
Administration c
has range
Pharmacologic Substance c

partecipateop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/partecipate

A clinical trial participation participates in a clinical trial.
has domain
Clinical Trial Participation c
has range
Clinical Trial c

pertainop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pertain

A clinical trial pertains clinics and hospitals.
has domain
Clinical Trial c
has range
Clinics and Hospitals c

relapseAssessmentop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseAssessment

Refers to the assessment related to a relapse.
has domain
Recurrent Disease c
has range
Intervention or Procedure c

requiresMRIop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/requiresMRI

When a relapse requires an MRI.

sameAs_ICD10op back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/sameAs_ICD10

has super-properties
same as op
is also defined as
annotation property

sameAsUMLSop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/sameAsUMLS

has super-properties
same as op
is also defined as
annotation property

siteop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/site

Site of onset.
has domain
Onset c
has range
anatomical structure c

surgicalAreaop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/surgicalArea

The area involved in a surgical procedure.
has domain
Surgical Procedure c
has range
anatomical structure c

symptomAreaop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/symptomArea

The area involved in a symptom.
has domain
Symptom c
has range
anatomical structure c

traumaAreaop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/traumaArea

The area involved in a trauma.
has domain
Injury c
has range
anatomical structure c

undergoop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/undergo

A patient undergoes an event.
has domain
Patient c
has range
Event c

Data Properties

activityTypedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/activityType

The type of physical activity carried out.
has domain
Physical Activity c
has range
langString

administrationRoutedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/administrationRoute

A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body.
has domain
Administration c
has range
langString

age_onsetdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/age_onset

Age of the patient at onset (expressed in years).
has domain
Onset c
has range
float

albumindp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/albumin

A quantitative measurement of albumin present in a sample of CSF. Unit of measure : [mg/l].
has domain
CSF Analysis c
has range
float

Albumin leveldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Albumin_level

A quantitative measurement of albumin present in a sample [defined in grams per decilitre (g/dL)].
has domain
Hematology Test c
has range
float

Albumin lower rangedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Albumin_lower_range

A lower range of albumin present in a sample [defined in grams per decilitre (g/dL)].
has domain
Hematology Test c
has range
float

Albumin upper rangedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Albumin_upper_range

An upper range of albumin present in a sample [defined in grams per decilitre (g/dL)].
has domain
Hematology Test c
has range
float

alivedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alive

The status indicating whether the patient is still alive.

has characteristics: functional

has domain
Patient c
has range
boolean

alsfrs-r-totdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs-r-tot

Revised Amyotrophic Lateral Sclerosis Functional Rating Scale. Sum of items 1,2,3,4,5,6,7,8,9,10,11 and 12.
has domain
ALSFRS-R c
has range
integer

alsfrs-totdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs-tot

Amyotrophic Lateral Sclerosis Functional Rating Scale. Sum of items 1,2,3,4,5,6,7,8,9 and old 10.
has domain
ALSFRS c
has range
integer

alsfrs_1dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_1

Item 1: speech.
has domain
ALSFRS c
ALSFRS-R c
has range
integer

alsfrs_10dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_10

Item 10: dyspnea.
has domain
ALSFRS-R c
has range
integer

alsfrs_11dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_11

Item 11: orthopnea.
has domain
ALSFRS-R c
has range
integer

alsfrs_12dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_12

Item 12: respiratory insufficiency.
has domain
ALSFRS-R c
has range
integer

alsfrs_2dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_2

Item 2: salivation.
has domain
ALSFRS c
ALSFRS-R c
has range
integer

alsfrs_3dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_3

Item 3: swallowing.
has domain
ALSFRS c
ALSFRS-R c
has range
integer

alsfrs_4dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_4

Item 4: handwriting.
has domain
ALSFRS c
ALSFRS-R c
has range
integer

alsfrs_5dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_5

Item 5: cutting food and handling utensils.
has domain
ALSFRS c
ALSFRS-R c
has range
integer

alsfrs_6dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_6

Item 6: dressing and hygiene.
has domain
ALSFRS c
ALSFRS-R c
has range
integer

alsfrs_7dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_7

Item 7: turning in bed and adjusting bed clothes.
has domain
ALSFRS c
ALSFRS-R c
has range
integer

alsfrs_8dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_8

Item 8: walking.
has domain
ALSFRS c
ALSFRS-R c
has range
integer

alsfrs_9dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_9

Item 9: climbing stairs.
has domain
ALSFRS c
ALSFRS-R c
has range
integer

alsfrs_old10dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs_old10

Item old 10: breathing.
has domain
ALSFRS c
has range
integer

ambulationdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ambulation

EDSS score that regards the ambulation.
has domain
Expanded Disability Status Scale c
has range

anti-chickenpox antibodydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/anti-chickenpox_antibody_test

has domain
Hematology Test c
has range
langString

anti-Tgdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/anti-Tg

A quantitative measurement for anti-Tg in a sample of blood. Unit of measure : [U/L].
has domain
Hematology Test c
has range
float

anti-TgNormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/anti-TgNormal

States if the value of anti-Tg observed in the blood test is normal or not.
has domain
Hematology Test c
has range
boolean

AOPabsolutedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/AOPabsolute

The airway occlusion pressure, P0.1, is the negative airway pressure generated during the first 100 msec of an occluded inspiration.
has domain
Pulmonary Function Test c
has range
float

AOPrelativedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/AOPrelative

The airway occlusion pressure, P0.1, is the negative airway pressure generated during the first 100 msec of an occluded inspiration.
has domain
Pulmonary Function Test c
has range
float

axialdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/axial

The part of the skeleton that includes the skull and spinal column and sternum and ribs. [Definition Source: NCI]
has domain
Onset c
has range
boolean

before20Yearsdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/before20Years

A patient who smoked before the age of 20.
has domain
Smoking c
has range
boolean

bloodAbTMSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAbTMS

A quantitative measurement of AbTMS present in a sample of blood. Unit of measure : [10e9/L].
has domain
Hematology Test c
has range
float

bloodAbTMSNormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAbTMSNormal

States if the value of AbTMS observed in the blood test is normal or not.
has domain
Hematology Test c
has range
boolean

bloodAlbuminNormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAlbuminNormal

States if the value of albumin observed in the blood test is normal or not.
has domain
Hematology Test c
has range
boolean

bloodAlkalinePhosphatasedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAlkalinePhosphatase

A quantitative measurement of alkaline phosphatase present in a sample of blood. Unit of measure : [U/L].
has domain
Hematology Test c
has range
integer

bloodAlkalinePhosphataseNormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAlkalinePhosphataseNormal

States if the value of alkaline phosphatase observed in the blood test is normal or not.
has domain
Hematology Test c
has range
boolean

bloodAMAdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAMA

has domain
Hematology Test c
has range
float

bloodAMANormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAMANormal

has domain
Hematology Test c
has range
boolean

bloodAmylaseNormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAmylaseNormal

States if the value of amylase observed in the blood test is normal or not.
has domain
Hematology Test c
has range
boolean

bloodANAdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodANA

has domain
Hematology Test c
has range
float

bloodANANormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodANANormal

has domain
Hematology Test c
has range
boolean

bloodANCAdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodANCA

has domain
Hematology Test c
has range
float

bloodANCANormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodANCANormal

has domain
Hematology Test c
has range
boolean

bloodAnti-cardiolipindp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAnti-cardiolipin

has domain
Hematology Test c
has range
float

bloodAnti-cardiolipinNormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAnti-cardiolipinNormal

has domain
Hematology Test c
has range
boolean

bloodAnti-DNAdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAnti-DNA

has domain
Hematology Test c
has range
float

bloodAnti-DNANormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAnti-DNANormal

has domain
Hematology Test c
has range
boolean

bloodAnti-LKMdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAnti-LKM

has domain
Hematology Test c
has range
float

bloodAnti-LKMNormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAnti-LKMNormal

has domain
Hematology Test c
has range
boolean

bloodAnti-SSA_Rodp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAnti-SSA_Ro

has domain
Hematology Test c
has range
float

bloodAnti-SSA_RoNormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAnti-SSA_RoNormal

has domain
Hematology Test c
has range
boolean

bloodAnti-transglutaminasedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAnti-transglutaminase

has domain
Hematology Test c
has range
float

bloodAnti-transglutaminaseNormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAnti-transglutaminaseNormal

has domain
Hematology Test c
has range
boolean

bloodAPCAdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAPCA

has domain
Hematology Test c
has range
float

bloodAPCANormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodAPCANormal

has domain
Hematology Test c
has range
boolean

bloodASMAdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodASMA

has domain
Hematology Test c
has range
float

bloodASMANormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodASMANormal

has domain
Hematology Test c
has range
boolean

bloodBasophildp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodBasophil

A percentage measure of eosinophil present in a sample of blood. Unit of measure : [%].
has domain
Hematology Test c
has range
float

bloodBasophilNormaldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bloodBasophilNormal

States if the value of basophil observed in the blood test is normal or not.
has domain
Hematology Test c
has range
boolean

bloodBilirubindp back to ToC